Q84V03 · PCH1_ARATH

Function

function

Together with PCHL, regulates growth and development adaptation to the ambient environment by controlling negatively phytochrome B (phyB) dark reversion, a temperature-dependent thermal relaxation process during which phyB reverts from the active to the inactive state (PubMed:29263319, PubMed:32061894).
Contributes to red (R) light-triggered photomorphogenesis (PubMed:29263319).
Promotes various light responses such as seed germination, hypocotyl gravitropism and chlorophyll biosynthesis, via direct interaction with PIF1 and COP1 (PubMed:32061894).
Prevents DNA-binding ability of PIF1 to negatively regulate the expressions of its target genes (PubMed:32061894).
Facilitates the physical interaction between phyB and PIF1 and the subsequent light-induced degradation of PIF1 (PubMed:32061894).

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Biological Processchloroplast organization
Biological Processcircadian rhythm
Biological Processpositive regulation of DNA-templated transcription
Biological Processregulation of photomorphogenesis

Names & Taxonomy

Protein names

  • Recommended name
    Protein PHOTOPERIODIC CONTROL OF HYPOCOTYL 1
  • Alternative names
    • F-box protein PCH1

Gene names

    • Name
      PCH1
    • ORF names
      F16F14.15
    • Ordered locus names
      At2g16365

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q84V03
  • Secondary accessions
    • Q1PF61
    • Q94B23
    • Q9SIW6

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Nucleus
Note: Observed in subnuclear light-induced structures called photobodies.

Keywords

Phenotypes & Variants

Disruption phenotype

Reduced seed germination in red (R) light; this phenotype is reversed in plants lacking PIF1 (PubMed:32061894).
Reduced PIF1 degradation in response to red light pulse (PubMed:32061894).
Hypersensitivity to gravity stimulus and increased greening (PubMed:32061894).
Increased hypocotyl growth independently of far-red (FR) pulse at light-off, as the result of a rapid loss of active phyB due to increased dark reversion (PubMed:29263319).
Suppression of cop1 phenotype in darkness (PubMed:32061894).
Highly unstable phyB-containing photobodies in plants lacking both PCH1 and PCHL (PubMed:29263319).

Variants

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The viewer provides 207 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003960641-778Protein PHOTOPERIODIC CONTROL OF HYPOCOTYL 1

Post-translational modification

Ubiquitinated by COP1 in darkness; this leads to proteasomal degradation.

Keywords

Proteomic databases

PTM databases

Expression

Tissue specificity

Mainly expressed in cotyledons, hypocotyls, leaves and roots.

Induction

Induced by far-red (FR) and blue (B) lights, as well as transiently following transition from darkness to red light (R) in a phyB-independent manner; responses to red and far-red lights depend on phyA, and responses to blue light rely on both phyA and cryptochromes (PubMed:29263319).
In the dark, binds to COP1 and undergo degradation through the 26S proteasome pathway (PubMed:32061894).

Gene expression databases

Interaction

Subunit

Interacts with light-activated phyB (PubMed:29263319).
Binds directly to PIF1 and COP1 (PubMed:32061894).

Protein-protein interaction databases

Family & Domains

Features

Showing features for compositional bias, region, domain.

Type
IDPosition(s)Description
Compositional bias74-91Polar residues
Region74-95Disordered
Region186-283Disordered
Compositional bias212-242Polar residues
Region316-335Disordered
Domain470-505F-box

Phylogenomic databases

Family and domain databases

Sequence & Isoforms

Align isoforms (3)
  • Sequence status
    Complete

This entry describes 3 isoforms produced by Alternative splicing.

Q84V03-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    778
  • Mass (Da)
    88,623
  • Last updated
    2010-08-10 v2
  • Checksum
    DC34D0EDACE92DF5
MSEHVMVLGKGNKGISKNSSVNPYESAWLGRWTQSGSEVKFHDGETNCSKQLIRPEDENHGVEVLPFPMFKVSQKRETTTTTTTKPSFHEDVGSSSRAMVNRMPWMYPQGENFSSSNRLDFPIQEKTTQNLLELIRPVRIYATVDSVNLPKEDSHQLLKGSTVSMKLKGKIFGGYLDLFPNQDHSHNRGGVRLQSLESSKDTQEDGPRKNESSAETNTLEMDRLQTIHLSGSISSSSTKGKGIKGYSAIPRTEIPDMNEEPPLVPDRENSVDGHQGETSNSATQSMNVEHFLSRDCKRVRLEPEVEASSRWVKRLKTSPSDSSETKSMMKMKEASLGEKENNNLFLEILKSGINNLQPRNQEPVVSQSNDLRQGGDDITLLHPWIQRWCKKKTTSTDQPTGQEASFEPESHKEFEKKQYPSIAAMALMGKALSGLNPYGLRKTNSLMVWNARDLSFTYRSLRWNLTMADWPLLPNDLLELIMGHLETSFEIFLFRSVCSSWRSVVPPLDHSRCLGIKTHDISFNVGFSFNGRPTNEYCTLKKIPIYLVKFWTPFGDDYLLAEMRERNDGEPKLLLSPLSSNGIKYGMGINKVLFNSLTSPIIPFGQYYEITYIEKRPSEYRFGFPYKLEWVEITERVEFLKLDSEDSRDFAVLFAGRMCNLVMYRSRNMSWTQVVEHPEKYAYQDLVAFKGKFYAVDSSGRGRVFVVELSFEVTEIPSVGGSQQSSKESLVQSGEELLLVQRFTPVGRRYDEYIYIHGSECLDLMKKEERESGFKLMT

Q84V03-2

Q84V03-3

Sequence caution

The sequence AAO73431.1 differs from that shown. Reason: Erroneous initiation Truncated N-terminus.

Features

Showing features for compositional bias, alternative sequence.

Type
IDPosition(s)Description
Compositional bias74-91Polar residues
Compositional bias212-242Polar residues
Alternative sequenceVSP_039574455in isoform 2
Alternative sequenceVSP_039573455-458in isoform 3
Alternative sequenceVSP_039575456-778in isoform 2
Alternative sequenceVSP_039576515-561in isoform 3

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC007047
EMBL· GenBank· DDBJ
AAD22304.2
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
AEC06484.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
AEC06485.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
AEC06486.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
AEC06487.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
ANM61300.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
ANM61301.1
EMBL· GenBank· DDBJ
Genomic DNA
AY042900
EMBL· GenBank· DDBJ
AAK68840.1
EMBL· GenBank· DDBJ
mRNA
BT006598
EMBL· GenBank· DDBJ
AAP31942.1
EMBL· GenBank· DDBJ
mRNA
AY227650
EMBL· GenBank· DDBJ
AAO73431.1
EMBL· GenBank· DDBJ
mRNA Different initiation
DQ446505
EMBL· GenBank· DDBJ
ABE65815.1
EMBL· GenBank· DDBJ
mRNA
AY773845
EMBL· GenBank· DDBJ
AAV63874.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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