Q84V03 · PCH1_ARATH
- ProteinProtein PHOTOPERIODIC CONTROL OF HYPOCOTYL 1
- GenePCH1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids778 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Together with PCHL, regulates growth and development adaptation to the ambient environment by controlling negatively phytochrome B (phyB) dark reversion, a temperature-dependent thermal relaxation process during which phyB reverts from the active to the inactive state (PubMed:29263319, PubMed:32061894).
Contributes to red (R) light-triggered photomorphogenesis (PubMed:29263319).
Promotes various light responses such as seed germination, hypocotyl gravitropism and chlorophyll biosynthesis, via direct interaction with PIF1 and COP1 (PubMed:32061894).
Prevents DNA-binding ability of PIF1 to negatively regulate the expressions of its target genes (PubMed:32061894).
Facilitates the physical interaction between phyB and PIF1 and the subsequent light-induced degradation of PIF1 (PubMed:32061894).
Contributes to red (R) light-triggered photomorphogenesis (PubMed:29263319).
Promotes various light responses such as seed germination, hypocotyl gravitropism and chlorophyll biosynthesis, via direct interaction with PIF1 and COP1 (PubMed:32061894).
Prevents DNA-binding ability of PIF1 to negatively regulate the expressions of its target genes (PubMed:32061894).
Facilitates the physical interaction between phyB and PIF1 and the subsequent light-induced degradation of PIF1 (PubMed:32061894).
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Biological Process | chloroplast organization | |
Biological Process | circadian rhythm | |
Biological Process | positive regulation of DNA-templated transcription | |
Biological Process | regulation of photomorphogenesis |
Names & Taxonomy
Protein names
- Recommended nameProtein PHOTOPERIODIC CONTROL OF HYPOCOTYL 1
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ84V03
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Note: Observed in subnuclear light-induced structures called photobodies.
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
Reduced seed germination in red (R) light; this phenotype is reversed in plants lacking PIF1 (PubMed:32061894).
Reduced PIF1 degradation in response to red light pulse (PubMed:32061894).
Hypersensitivity to gravity stimulus and increased greening (PubMed:32061894).
Increased hypocotyl growth independently of far-red (FR) pulse at light-off, as the result of a rapid loss of active phyB due to increased dark reversion (PubMed:29263319).
Suppression of cop1 phenotype in darkness (PubMed:32061894).
Highly unstable phyB-containing photobodies in plants lacking both PCH1 and PCHL (PubMed:29263319).
Reduced PIF1 degradation in response to red light pulse (PubMed:32061894).
Hypersensitivity to gravity stimulus and increased greening (PubMed:32061894).
Increased hypocotyl growth independently of far-red (FR) pulse at light-off, as the result of a rapid loss of active phyB due to increased dark reversion (PubMed:29263319).
Suppression of cop1 phenotype in darkness (PubMed:32061894).
Highly unstable phyB-containing photobodies in plants lacking both PCH1 and PCHL (PubMed:29263319).
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 207 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000396064 | 1-778 | Protein PHOTOPERIODIC CONTROL OF HYPOCOTYL 1 | ||
Post-translational modification
Ubiquitinated by COP1 in darkness; this leads to proteasomal degradation.
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Tissue specificity
Mainly expressed in cotyledons, hypocotyls, leaves and roots.
Induction
Induced by far-red (FR) and blue (B) lights, as well as transiently following transition from darkness to red light (R) in a phyB-independent manner; responses to red and far-red lights depend on phyA, and responses to blue light rely on both phyA and cryptochromes (PubMed:29263319).
In the dark, binds to COP1 and undergo degradation through the 26S proteasome pathway (PubMed:32061894).
In the dark, binds to COP1 and undergo degradation through the 26S proteasome pathway (PubMed:32061894).
Gene expression databases
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 74-91 | Polar residues | |||
Region | 74-95 | Disordered | |||
Region | 186-283 | Disordered | |||
Compositional bias | 212-242 | Polar residues | |||
Region | 316-335 | Disordered | |||
Domain | 470-505 | F-box | |||
Phylogenomic databases
Family and domain databases
Sequence & Isoforms
- Sequence statusComplete
This entry describes 3 isoforms produced by Alternative splicing.
Q84V03-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length778
- Mass (Da)88,623
- Last updated2010-08-10 v2
- ChecksumDC34D0EDACE92DF5
Q84V03-2
- Name2
Q84V03-3
- Name3
Sequence caution
Features
Showing features for compositional bias, alternative sequence.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 74-91 | Polar residues | |||
Compositional bias | 212-242 | Polar residues | |||
Alternative sequence | VSP_039574 | 455 | in isoform 2 | ||
Alternative sequence | VSP_039573 | 455-458 | in isoform 3 | ||
Alternative sequence | VSP_039575 | 456-778 | in isoform 2 | ||
Alternative sequence | VSP_039576 | 515-561 | in isoform 3 | ||
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC007047 EMBL· GenBank· DDBJ | AAD22304.2 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002685 EMBL· GenBank· DDBJ | AEC06484.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002685 EMBL· GenBank· DDBJ | AEC06485.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002685 EMBL· GenBank· DDBJ | AEC06486.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002685 EMBL· GenBank· DDBJ | AEC06487.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002685 EMBL· GenBank· DDBJ | ANM61300.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002685 EMBL· GenBank· DDBJ | ANM61301.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY042900 EMBL· GenBank· DDBJ | AAK68840.1 EMBL· GenBank· DDBJ | mRNA | ||
BT006598 EMBL· GenBank· DDBJ | AAP31942.1 EMBL· GenBank· DDBJ | mRNA | ||
AY227650 EMBL· GenBank· DDBJ | AAO73431.1 EMBL· GenBank· DDBJ | mRNA | Different initiation | |
DQ446505 EMBL· GenBank· DDBJ | ABE65815.1 EMBL· GenBank· DDBJ | mRNA | ||
AY773845 EMBL· GenBank· DDBJ | AAV63874.1 EMBL· GenBank· DDBJ | mRNA |