Q84TI6 · CDKE1_ARATH
- ProteinCyclin-dependent kinase E-1
- GeneCDKE-1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids470 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Involved in cell differentiation. Required for the specification of stamen and carpel identities and for the proper termination of stem cells in the floral meristem.
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | ATP binding | |
Molecular Function | cyclin-dependent protein serine/threonine kinase activity | |
Molecular Function | kinase binding | |
Molecular Function | protein serine kinase activity | |
Molecular Function | RNA polymerase II CTD heptapeptide repeat kinase activity | |
Biological Process | cell division |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCyclin-dependent kinase E-1
- EC number
- Short namesCDKE;1
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ84TI6
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000293122 | 1-470 | Cyclin-dependent kinase E-1 | |||
Sequence: MGDGSSSRSNSSNSTSEKPEWLQQYNLVGKIGEGTYGLVFLARTKTPPKRPIAIKKFKQSKDGDGVSPTAIREIMLLREISHENVVKLVNVHINFADMSLYLAFDYAEYDLYEIIRHHRDKVGHSLNTYTVKSLLWQLLNGLNYLHSNWIIHRDLKPSNILVMGDAEEHGIVKIADFGLARIYQAPLKPLSDNGVVVTIWYRAPELLLGSKHYTSAVDMWAVGCIFAELLTLKPLFQGAEAKSSQNPFQLDQLDKIFKILGHPTMDKWPTLVNLPHWQNDVQHIQAHKYDSVGLHNVVHLNQKSPAYDLLSKMLEYDPLKRITASQALEHEYFRMDPLPGRNAFVASQPMEKNVNYPTRPVDTNTDFEGTTSINPPQAVAAGNVAGNMAGAHGMGSRSMPRPMVAHNMQRMQQSQGMMAYNFPAQAGLNPSVPLQQQRGMAQPHQQQQLRRKDPGMGMSGYAPPNKSRRL | ||||||
Modified residue | 36 | Phosphotyrosine | ||||
Sequence: Y |
Keywords
- PTM
Proteomic databases
Expression
Tissue specificity
Expressed in roots, leaves and stems. Expressed in young dividing tissue, such as shoot and root tips, lateral root primordia, young leaves and flowers. Expressed in the inflorescence meristem, inflorescence stem and young flowers.
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain, compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 25-333 | Protein kinase | ||||
Sequence: YNLVGKIGEGTYGLVFLARTKTPPKRPIAIKKFKQSKDGDGVSPTAIREIMLLREISHENVVKLVNVHINFADMSLYLAFDYAEYDLYEIIRHHRDKVGHSLNTYTVKSLLWQLLNGLNYLHSNWIIHRDLKPSNILVMGDAEEHGIVKIADFGLARIYQAPLKPLSDNGVVVTIWYRAPELLLGSKHYTSAVDMWAVGCIFAELLTLKPLFQGAEAKSSQNPFQLDQLDKIFKILGHPTMDKWPTLVNLPHWQNDVQHIQAHKYDSVGLHNVVHLNQKSPAYDLLSKMLEYDPLKRITASQALEHEYF | ||||||
Compositional bias | 428-449 | Polar residues | ||||
Sequence: LNPSVPLQQQRGMAQPHQQQQL | ||||||
Region | 428-470 | Disordered | ||||
Sequence: LNPSVPLQQQRGMAQPHQQQQLRRKDPGMGMSGYAPPNKSRRL |
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length470
- Mass (Da)52,797
- Last updated2007-07-10 v2
- Checksum85A92D0000FD5E46
Sequence caution
Features
Showing features for compositional bias, sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 428-449 | Polar residues | ||||
Sequence: LNPSVPLQQQRGMAQPHQQQQL | ||||||
Sequence conflict | 452 | in Ref. 4; AAO64158 and 6; BAF00561 | ||||
Sequence: K → E |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AY600243 EMBL· GenBank· DDBJ | AAT36644.1 EMBL· GenBank· DDBJ | mRNA | ||
AB005234 EMBL· GenBank· DDBJ | BAB10454.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002688 EMBL· GenBank· DDBJ | AED97776.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BT005753 EMBL· GenBank· DDBJ | AAO64158.1 EMBL· GenBank· DDBJ | mRNA | ||
BT020376 EMBL· GenBank· DDBJ | AAV85731.1 EMBL· GenBank· DDBJ | mRNA | ||
AK228654 EMBL· GenBank· DDBJ | BAF00561.1 EMBL· GenBank· DDBJ | mRNA | ||
AJ439879 EMBL· GenBank· DDBJ | CAD29165.1 EMBL· GenBank· DDBJ | mRNA | Frameshift |