Q84TI6 · CDKE1_ARATH

Function

function

Involved in cell differentiation. Required for the specification of stamen and carpel identities and for the proper termination of stem cells in the floral meristem.

Catalytic activity

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site31-39ATP (UniProtKB | ChEBI)
Binding site55ATP (UniProtKB | ChEBI)
Active site154Proton acceptor

GO annotations

AspectTerm
Cellular Componentnucleus
Molecular FunctionATP binding
Molecular Functioncyclin-dependent protein serine/threonine kinase activity
Molecular Functionkinase binding
Molecular Functionprotein serine kinase activity
Molecular FunctionRNA polymerase II CTD heptapeptide repeat kinase activity
Biological Processcell division

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Cyclin-dependent kinase E-1
  • EC number
  • Short names
    CDKE;1
  • Alternative names
    • Cyclin-dependent kinase 8
    • Protein HUA ENHANCER 3

Gene names

    • Name
      CDKE-1
    • Synonyms
      CDK8, HEN3
      , RAO1
    • ORF names
      MBK5.8
    • Ordered locus names
      At5g63610

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q84TI6
  • Secondary accessions
    • Q70Z09
    • Q9FFQ3

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain, modified residue.

TypeIDPosition(s)Description
ChainPRO_00002931221-470Cyclin-dependent kinase E-1
Modified residue36Phosphotyrosine

Keywords

Proteomic databases

Expression

Tissue specificity

Expressed in roots, leaves and stems. Expressed in young dividing tissue, such as shoot and root tips, lateral root primordia, young leaves and flowers. Expressed in the inflorescence meristem, inflorescence stem and young flowers.

Gene expression databases

Interaction

Subunit

Interacts with MED14, HDA19 and LUG. Interacts with KIN10 (PubMed:23229550).

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain, compositional bias, region.

TypeIDPosition(s)Description
Domain25-333Protein kinase
Compositional bias428-449Polar residues
Region428-470Disordered

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    470
  • Mass (Da)
    52,797
  • Last updated
    2007-07-10 v2
  • Checksum
    85A92D0000FD5E46
MGDGSSSRSNSSNSTSEKPEWLQQYNLVGKIGEGTYGLVFLARTKTPPKRPIAIKKFKQSKDGDGVSPTAIREIMLLREISHENVVKLVNVHINFADMSLYLAFDYAEYDLYEIIRHHRDKVGHSLNTYTVKSLLWQLLNGLNYLHSNWIIHRDLKPSNILVMGDAEEHGIVKIADFGLARIYQAPLKPLSDNGVVVTIWYRAPELLLGSKHYTSAVDMWAVGCIFAELLTLKPLFQGAEAKSSQNPFQLDQLDKIFKILGHPTMDKWPTLVNLPHWQNDVQHIQAHKYDSVGLHNVVHLNQKSPAYDLLSKMLEYDPLKRITASQALEHEYFRMDPLPGRNAFVASQPMEKNVNYPTRPVDTNTDFEGTTSINPPQAVAAGNVAGNMAGAHGMGSRSMPRPMVAHNMQRMQQSQGMMAYNFPAQAGLNPSVPLQQQRGMAQPHQQQQLRRKDPGMGMSGYAPPNKSRRL

Sequence caution

The sequence CAD29165.1 differs from that shown. Reason: Frameshift

Features

Showing features for compositional bias, sequence conflict.

TypeIDPosition(s)Description
Compositional bias428-449Polar residues
Sequence conflict452in Ref. 4; AAO64158 and 6; BAF00561

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY600243
EMBL· GenBank· DDBJ
AAT36644.1
EMBL· GenBank· DDBJ
mRNA
AB005234
EMBL· GenBank· DDBJ
BAB10454.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002688
EMBL· GenBank· DDBJ
AED97776.1
EMBL· GenBank· DDBJ
Genomic DNA
BT005753
EMBL· GenBank· DDBJ
AAO64158.1
EMBL· GenBank· DDBJ
mRNA
BT020376
EMBL· GenBank· DDBJ
AAV85731.1
EMBL· GenBank· DDBJ
mRNA
AK228654
EMBL· GenBank· DDBJ
BAF00561.1
EMBL· GenBank· DDBJ
mRNA
AJ439879
EMBL· GenBank· DDBJ
CAD29165.1
EMBL· GenBank· DDBJ
mRNA Frameshift

Genome annotation databases

Similar Proteins

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