Q84LQ5 · Q84LQ5_SORBI
- ProteinMalic enzyme
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids636 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
Cofactor
Protein has several cofactor binding sites:
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )
Note: Divalent metal cations. Prefers magnesium or manganese.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 184 | Proton donor | ||||
Sequence: Y | ||||||
Binding site | 237 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 237 | substrate | ||||
Sequence: R | ||||||
Active site | 255 | Proton acceptor | ||||
Sequence: K | ||||||
Binding site | 255 | pyruvate (UniProtKB | ChEBI) | ||||
Sequence: K | ||||||
Binding site | 327 | a divalent metal cation (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 328 | a divalent metal cation (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 331 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: N | ||||||
Binding site | 351 | a divalent metal cation (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 384 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: A | ||||||
Binding site | 386 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 387 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: A | ||||||
Binding site | 419 | NADP+ (UniProtKB | ChEBI); covalent | ||||
Sequence: S | ||||||
Binding site | 420 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: K | ||||||
Binding site | 421 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 435 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: K | ||||||
Binding site | 490 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: L | ||||||
Binding site | 492 | pyruvate (UniProtKB | ChEBI) | ||||
Sequence: N | ||||||
Binding site | 492 | substrate | ||||
Sequence: N | ||||||
Binding site | 535 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: S | ||||||
Binding site | 536 | substrate | ||||
Sequence: N |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | chloroplast | |
Molecular Function | malate dehydrogenase (decarboxylating) (NADP+) activity | |
Molecular Function | metal ion binding | |
Molecular Function | NAD binding | |
Biological Process | malate metabolic process | |
Biological Process | pyruvate metabolic process |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Recommended nameMalic enzyme
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > PACMAD clade > Panicoideae > Andropogonodae > Andropogoneae > Sorghinae > Sorghum
Accessions
- Primary accessionQ84LQ5
Proteomes
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 161-342 | Malic enzyme N-terminal | ||||
Sequence: QETDERLFYKLLIENVVELLPYVYTPTVGEACQKYGSIFGRPQGLYVSLKDKGRVLEVLRNWPHRNVQVICVTDGERILGLGDLGCQGMGIPVGKLALYTALGGVDPSACLPITIDVGTNNEKLLNDEFYIGLRQKRARGEEYDELMEEFMAAVKTFYGEKVLIQFEDFANHNAFDLLEKYS | ||||||
Domain | 352-605 | Malic enzyme NAD-binding | ||||
Sequence: IQGTASVVLAGLLAALKMVGGTLAEQTYLFLGAGEAGTGIAELIALEMSKQTKAPIEECRKKVWLVDSKGLIVDSRKSSLAPFKKPWAHEHEPLTTLYDAVQSIKPTVLIGTSGVGRTFTKEIVEAMASINERPIIFSLSNPTSHSECTAEQAYTWTQGRAVFASGSPFAPVEYDGKTFVPGQSNNAYIFPGLGLGLVISGAVRVHEDMLLAASAALADQATEENFVTGSIFPPFTNIRKISAYIAAAVAAKAY |
Sequence similarities
Belongs to the malic enzymes family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length636
- Mass (Da)69,378
- Last updated2003-06-01 v1
- Checksum98B86228066D7996
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AY274836 EMBL· GenBank· DDBJ | AAP32204.1 EMBL· GenBank· DDBJ | mRNA | ||
CM000762 EMBL· GenBank· DDBJ | EES00150.1 EMBL· GenBank· DDBJ | Genomic DNA |