Q84365 · Q84365_MUMIP

Function

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for active site.

1721100200300400500600700
TypeIDPosition(s)Description
Active site259For nuclease activity

GO annotations

AspectTerm
Cellular Componenthost cell nucleus
Molecular FunctionATP binding
Molecular FunctionDNA binding
Molecular Functionendonuclease activity
Molecular Functionhelicase activity
Molecular Functionmetal ion binding
Biological ProcessDNA replication
Biological Processsymbiont-mediated arrest of host cell cycle during G2/M transition
Biological Processsymbiont-mediated perturbation of host apoptosis
Biological Processsymbiont-mediated perturbation of host cell cycle G1/S transition checkpoint
Biological Processviral DNA genome replication

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Initiator protein NS1
  • EC number
  • Alternative names
    • NCVP1
    • Non-capsid protein NS-1
    • Non-structural protein NS1

Gene names

    • Name
      NS1

Organism names

Accessions

  • Primary accession
    Q84365

Proteomes

Subcellular Location

Keywords

PTM/Processing

Keywords

Structure

3D structure databases

Family & Domains

Features

Showing features for domain, motif, region, compositional bias.

Type
IDPosition(s)Description
Domain70-308PV NS1-Nuc
Motif176-178RCR-2
Motif259-263RCR-3
Domain422-577SF3 helicase
Region662-692Disordered
Compositional bias664-692Polar residues

Sequence similarities

Belongs to the parvoviruses initiator protein NS1 family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    721
  • Mass (Da)
    81,896
  • Last updated
    1996-11-01 v1
  • Checksum
    18391758E42F0DCF
MISGSGSLNQGAKRKWAWFKVYKQLLKSVTYLFFHSVSRDAQKESNQLTMAGNAYSDEVLGATNWLKEKSNQEVFSFVFKNENVQLNGKDIGWNSYKKELQEDELKSLQRGAETTWDQSEDMEWETTVDEMTKKQVFIFDSLVKKCLFEVLNTKNIFPGDVNWFVQHEWGKDQGWHCHVLIGGKDFSQAQGKWWRRQLNVYWSRWLVTACNVQLTPAERIKLREIAEDNEWVTLLTYKHKQTKKDYTKCVLFGNMIAYYFLTKKKISTSPPRDGGYFLSSDSGWKTNFLKEGERHLVSKLYTDDMRPETVETTVTTAQETKRGRIQTKKEVSIKTTLKELVHKRVTSPEDWMMMQPDSYIEMMAQPGGENLLKNTLEICTLTLARTKTAFDLILEKAETSKLTNFSLPDTRTCRIFAFHGWNYVKVCHAICCVLNRQGGKRNTVLFHGPASTGKSIIAQAIAQAVGNVGCYNAANVNFPFNDCTNKNLIWVEEAGNFGQQVNQFKAICSGQTIRIDQKGKGSKQIEPTPVIMTTNENITVVRIGCEERPEHTQPIRDRMLNIHLTHTLPGDFGLVDKNEWPMICAWLVKNGYQSTMASYCAKWGKVPDWSENWAEPKVPTPINLLGSARSPFTTPKSTPLSQNYALTPLASDLEDLALEPWSTPNTPVAGTAETQNTGEAGSKACQDGQLSPTWSEIEEDLRACFGAEPLKKDFSEPLNLD

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
P03134NS1_MUMIPNS1672

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias664-692Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
J02275
EMBL· GenBank· DDBJ
AAA67108.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help