Q837J0 · Q837J0_ENTFA
- ProteinAlanine racemase
- Genealr
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids371 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.
Catalytic activity
- L-alanine = D-alanine
Cofactor
Pathway
Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 40 | Proton acceptor; specific for D-alanine | ||||
Sequence: K | ||||||
Binding site | 40 | pyridoxal 5'-phosphate (UniProtKB | ChEBI); covalent | ||||
Sequence: K | ||||||
Binding site | 44 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | ||||
Sequence: Y | ||||||
Binding site | 139 | substrate | ||||
Sequence: R | ||||||
Binding site | 207 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | ||||
Sequence: S | ||||||
Binding site | 222 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 224 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 225 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | ||||
Sequence: V | ||||||
Active site | 267 | Proton acceptor; specific for L-alanine | ||||
Sequence: Y | ||||||
Binding site | 314 | substrate | ||||
Sequence: M | ||||||
Binding site | 356 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | ||||
Sequence: Y |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | alanine racemase activity | |
Molecular Function | pyridoxal phosphate binding | |
Biological Process | D-alanine biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAlanine racemase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Enterococcaceae > Enterococcus
Accessions
- Primary accessionQ837J0
Proteomes
PTM/Processing
Features
Showing features for modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Modified residue | 40 | N6-(pyridoxal phosphate)lysine | ||||
Sequence: K |
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 246-371 | Alanine racemase C-terminal | ||||
Sequence: ALRLTSELIHVKRLAAGEGIGYGETYVTEAEEWIGTVPIGYADGWLRHLQGFTVLVNGKRCEIVGRVCMDQCMIRLAEEVPVGSVVTLVGKDGNEENTLQMVAEKLETIHYEVACTFSQRIPREYN |
Sequence similarities
Belongs to the alanine racemase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length371
- Mass (Da)40,980
- Last updated2003-06-01 v1
- Checksum4DE356FE62478E0B
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE016830 EMBL· GenBank· DDBJ | AAO80661.1 EMBL· GenBank· DDBJ | Genomic DNA |