Q827L9 · RISB_STRAW

Function

function

Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

Catalytic activity

Pathway

Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site265-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site58-605-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site81-835-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site86-87(2S)-2-hydroxy-3-oxobutyl phosphate (UniProtKB | ChEBI)
Active site89Proton donor
Binding site1145-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site128(2S)-2-hydroxy-3-oxobutyl phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentriboflavin synthase complex
Molecular Function6,7-dimethyl-8-ribityllumazine synthase activity
Biological Processriboflavin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    6,7-dimethyl-8-ribityllumazine synthase
  • EC number
  • Short names
    DMRL synthase
    ; LS
    ; Lumazine synthase

Gene names

    • Name
      ribH
    • Ordered locus names
      SAV_6905

Organism names

Accessions

  • Primary accession
    Q827L9

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001348151-1616,7-dimethyl-8-ribityllumazine synthase

Structure

Family & Domains

Sequence similarities

Belongs to the DMRL synthase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    161
  • Mass (Da)
    16,809
  • Last updated
    2003-06-01 v1
  • Checksum
    99201DF61C43C13D
MSGKGAPELSVRNCGDLRVAVIAAQWHEKVMDGLVDGALRALHELGIDEPTLLRVPGSFELPVVAKVLAGRGYDAIVALGVVIRGGTPHFDFVCQGVTQGLTQVSVDTGVPVGFGVLTCDTEEQALDRAGIEGSHEDKGHEAVTAAVATAATLRSVSEPWR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BA000030
EMBL· GenBank· DDBJ
BAC74616.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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