Q810B9 · SLIK3_MOUSE

  • Protein
    SLIT and NTRK-like protein 3
  • Gene
    Slitrk3
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    5/5

Function

function

Suppresses neurite outgrowth.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcell surface
Cellular ComponentGABA-ergic synapse
Cellular Componentmembrane
Cellular Componentpostsynaptic density membrane
Cellular Componentpostsynaptic membrane
Biological Processaxonogenesis
Biological Processgephyrin clustering involved in postsynaptic density assembly
Biological Processneurotransmitter-gated ion channel clustering
Biological Processpositive regulation of synapse assembly
Biological Processpostsynaptic density assembly
Biological Processregulation of presynapse assembly
Biological Processsynaptic membrane adhesion
Biological Processsynaptic transmission, GABAergic
Biological Processterminal button organization

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    SLIT and NTRK-like protein 3

Gene names

    • Name
      Slitrk3

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q810B9
  • Secondary accessions
    • Q6NZM5

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain30-655Extracellular
Transmembrane656-676Helical
Topological domain677-980Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for signal, chain, glycosylation.

TypeIDPosition(s)Description
Signal1-27
ChainPRO_000003267828-980SLIT and NTRK-like protein 3
Glycosylation69N-linked (GlcNAc...) asparagine
Glycosylation597N-linked (GlcNAc...) asparagine

Keywords

Proteomic databases

PTM databases

Expression

Tissue specificity

Broadly expressed in embryonic brain with highest expression in cortical plate, pyramidal cell layer of the hippocampus, thalamus and hypothalamus.

Gene expression databases

Interaction

Protein-protein interaction databases

Miscellaneous

Structure

Family & Domains

Features

Showing features for repeat, domain, region, compositional bias.

TypeIDPosition(s)Description
Repeat79-100LRR 1
Repeat103-124LRR 2
Repeat127-148LRR 3
Repeat151-172LRR 4
Repeat175-196LRR 5
Repeat198-219LRR 6
Domain233-284LRRCT 1
Region326-361Disordered
Compositional bias338-361Pro residues
Domain365-407LRRNT
Repeat410-431LRR 7
Repeat434-455LRR 8
Repeat458-479LRR 9
Repeat482-503LRR 10
Repeat506-527LRR 11
Repeat529-550LRR 12
Domain563-614LRRCT 2
Region622-644Disordered
Region709-735Disordered
Region762-785Disordered

Sequence similarities

Belongs to the SLITRK family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    980
  • Mass (Da)
    109,406
  • Last updated
    2011-07-27 v2
  • Checksum
    C7671B133C601314
MMKPSIAEMLHRGRMLWIILLSTIALGWTTPIPLIEDSEEIDEPCFDPCYCEVKESLFHIHCDSKGFTNISQITEFWSRPFKLYLQRNSMRRLYTNSFLHLNNAVSINLGNNALQDIQTGAFNGLKILKRLYLHENKLDVFRNDTFLGLESLEYLQADYNVIKRIESGAFRNLSKLRVLILNDNLIPVLPTNLFKAVSLTHLDLRGNRLKVLFYRGMLDHIGRSLMELQLEENPWNCTCEIVQLKSWLERIPYTALVGDITCETPFHFHGKDLREIKKTELCPLLSDSEVEASLGIPHLSSSKENAWPTKPSSMLSSVHFTASSVEYKSSNKQPKPTKQPRTPRPPSTSQALYPGPNQPPIAPYQTRPPIPIICPTGCTCNLHINDLGLTVNCKERGFNNISELLPRPLNAKKLYLSSNLIQKIYRSDFWNFSSLDLLHLGNNRISYVQDGAFINLPNLKSLFLNGNDIEKLTPGMFRGLQSLHYLYFEFNVIREIQPAAFSLMPNLKLLFLNNNLLRTLPTDAFAGTSLARLNLRKNYFLYLPVAGVLEHLNAIVQIDLNENPWDCTCDLVPFKQWIETISSVSVVGDVLCRTPENLTHRDVRTIELEVLCPEMLHIAQPGPSPPQPGDYHPNGGPTSASPYEFSPPGGPVPLSVLILSLLVLFFSAVFVAAGLFAYVLRRRRKKLPFRSKRQEGVDLTGIQMQCHRLFEDSGGNSGGSGGGGRPTLSSPEKAPPVGHVYEYIPHPVTQMCNNPIYKPREEEEVAASAAQDTGATDRGGPGTQPTGMAEVLLGSEQFAETPKENHSNYRTLLEKEKEWALAVSNSQLNTIVTVNHHHPHPHHSAVGGVSGVGGGTGGDLAGFRHHEKNGGVVLFPPGGGCGGGSLLLDRERPQPAPCTVGFVDCLYGTVPKLKELHVHPPGMQYPDLQQDARLKETLLFSAGKGFTDHQTPKSDYLDLRAKLQTKPDYLEVLEKTAYRF

Features

Showing features for compositional bias, sequence conflict.

TypeIDPosition(s)Description
Compositional bias338-361Pro residues
Sequence conflict636in Ref. 1; BAC67206
Sequence conflict690in Ref. 1; BAC67206
Sequence conflict721-723in Ref. 1; BAC67206
Sequence conflict732in Ref. 1; BAC67206
Sequence conflict735in Ref. 1; BAC67206
Sequence conflict977in Ref. 1; BAC67206

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB097572
EMBL· GenBank· DDBJ
BAC67206.1
EMBL· GenBank· DDBJ
Genomic DNA
AK158856
EMBL· GenBank· DDBJ
BAE34696.1
EMBL· GenBank· DDBJ
mRNA
CH466547
EMBL· GenBank· DDBJ
EDL15486.1
EMBL· GenBank· DDBJ
Genomic DNA
BC066059
EMBL· GenBank· DDBJ
AAH66059.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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