The mouse secreted gel-forming mucin gene cluster.Escande F., Porchet N., Bernigaud A., Petitprez D., Aubert J.-P., Buisine M.-P.View abstractCited forNUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-1442 AND 3655-4576, TISSUE SPECIFICITYStrainC57BL/6JCategoriesSequences, ExpressionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCBiochim. Biophys. Acta 1676:240-250 (2004)Cited in23Mapped to24
Gastrointestinal expression and partial cDNA cloning of murine Muc2.van Klinken B.J.-W., Einerhand A.W.C., Duits L.A., Makkink M.K., Tytgat K.M.A.J., Renes I.B., Verburg M., Bueller H.A., Dekker J.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA] OF 1-301, TISSUE SPECIFICITY, GLYCOSYLATIONStrain129TissueColonCategoriesPTM / Processing, Sequences, ExpressionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCAm. J. Physiol. 276:G115-G124 (1999)Cited in1Mapped to6
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).The MGC Project TeamView abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2809-3654 AND 3691-4576StrainFVB/NTissueColonCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenome Res. 14:2121-2127 (2004)Cited in99+99+
The transcriptional landscape of the mammalian genome.Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B.[...], Hayashizaki Y.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 4095-4576StrainC57BL/6JTissueSmall intestineCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCScience 309:1559-1563 (2005)Cited in99+16Mapped to99+
Colorectal cancer in mice genetically deficient in the mucin Muc2.Velcich A., Yang W., Heyer J., Fragale A., Nicholas C., Viani S., Kucherlapati R., Lipkin M., Yang K., Augenlicht L.View abstractCited forDISRUPTION PHENOTYPECategoriesPhenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCScience 295:1726-1729 (2002)Cited in1Mapped to36
The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria.Johansson M.E.V., Phillipson M., Petersson J., Velcich A., Holm L., Hansson G.C.View abstractCited forFUNCTION, SUBCELLULAR LOCATION, DISRUPTION PHENOTYPECategoriesFunction, Phenotypes & Variants, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 105:15064-15069 (2008)Cited in1Mapped to8
Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp protein.Johansson M.E.V., Thomsson K.A., Hansson G.C.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY, FUNCTION, INTERACTION WITH FCGBP, SUBCELLULAR LOCATIONCategoriesFunction, Sequences, Interaction, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Proteome Res. 8:3549-3557 (2009)Cited in3Mapped to24
Proximal colon-derived O-glycosylated mucus encapsulates and modulates the microbiota.Bergstrom K., Shan X., Casero D., Batushansky A., Lagishetty V., Jacobs J.P., Hoover C., Kondo Y., Shao B.[...], Xia L.View abstractCited forFUNCTION, GLYCOSYLATIONCategoriesFunction, PTM / ProcessingSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCScience 370:467-472 (2020)Cited in1Mapped to7
REGgamma Mitigates Radiation-Induced Enteritis by Preserving Mucin Secretion and Sustaining Microbiome Homeostasis.Zhu X., Li Y., Tian X., Jing Y., Wang Z., Yue L., Li J., Wu L., Zhou X.[...], Zhang B.View abstractAnnotationREGgamma Mitigates Radiation-Induced Enteritis by Preserving Mucin Secretion and Sustaining Microbiome Homeostasis.SourceGeneRif: 17831PubMedEurope PMCAm J Pathol 194:975-988 (2024)Mapped to30
Extracellular Matrix Orchestration of Tissue Remodeling in the Chronically Inflamed Mouse Colon.Moutin E.B., Bons J., Giavara G., Lourenco F., Pan D., Burton J.B., Shah S., Colombe M., Gascard P.[...], Winton D.J.View abstractCategoriesFunctionSourceMGI: 1339364PubMedEurope PMCCell Mol Gastroenterol Hepatol 17:639-656 (2024)Mapped to7
Differential Gene Expression of Checkpoint Markers and Cancer Markers in Mouse Models of Spontaneous Chronic Colitis.Ephraim R., Fraser S., Devereaux J., Stavely R., Feehan J., Eri R., Nurgali K., Apostolopoulos V.View abstractCategoriesFunctionSourceMGI: 1339364PubMedEurope PMCCancers (Basel) 15:4793-4793 (2023)Mapped to7
A binary module for microbiota-mediated regulation of gammadelta17 cells, hallmarked by microbiota-driven expression of programmed cell death protein 1.Huang H.I., Xue Y., Jewell M.L., Tan C.Y., Theriot B., Aggarwal N., Dockterman J., Lin Y.D., Schroeder E.A.[...], Hammer G.E.View abstractSourceMGI: 1339364PubMedEurope PMCCell Rep 42:112951-112951 (2023)Mapped to9
Spontaneous episodic inflammation in the intestines of mice lacking HNF4A is driven by microbiota and associated with early life microbiota alterations.Kelly C., Jawahar J., Davey L., Everitt J.I., Galanko J.A., Anderson C., Avendano J.E., McCann J.R., Sartor R.B.[...], Rawls J.F.View abstractCategoriesFunctionSourceMGI: 1339364PubMedEurope PMCmBio 14:e0150423-e0150423 (2023)Mapped to16
Sialylation shapes mucus architecture inhibiting bacterial invasion in the colon.Taniguchi M., Okumura R., Matsuzaki T., Nakatani A., Sakaki K., Okamoto S., Ishibashi A., Tani H., Horikiri M.[...], Takeda K.View abstractCategoriesFunctionSourceMGI: 1339364PubMedEurope PMCMucosal Immunol 16:624-641 (2023)Mapped to17
IgGFc-binding protein and MUC2 mucin produced by colonic goblet-like cells spatially interact non-covalently and regulate wound healing.Gorman H., Moreau F., Dufour A., Chadee K.View abstractAnnotationIgGFc-binding protein and MUC2 mucin produced by colonic goblet-like cells spatially interact non-covalently and regulate wound healing.CategoriesFunction, Subcellular LocationSourceGeneRif: 17831, MGI: 1339364PubMedEurope PMCFront Immunol 14:1211336-1211336 (2023)Mapped to9
Muc2-dependent microbial colonization of the jejunal mucus layer is diet sensitive and confers local resistance to enteric pathogen infection.Birchenough G.M.H., Schroeder B.O., Sharba S., Arike L., Recktenwald C.V., Puertolas-Balint F., Subramani M.V., Hansson K.T., Yilmaz B.[...], Hansson G.C.View abstractAnnotationMuc2-dependent microbial colonization of the jejunal mucus layer is diet sensitive and confers local resistance to enteric pathogen infection.CategoriesFunctionSourceGeneRif: 17831, MGI: 1339364PubMedEurope PMCCell Rep 42:112084-112084 (2023)Mapped to11
General transcription factor TAF4 antagonizes epigenetic silencing by Polycomb to maintain intestine stem cell functions.Saisa-Borreill S., Davidson G., Kleiber T., Thevenot A., Martin E., Mondot S., Blottiere H., Helleux A., Mengus G.[...], Freund J.N.View abstractCategoriesFunctionSourceMGI: 1339364PubMedEurope PMCCell Death Differ 30:839-853 (2023)Mapped to75
L-fucose reduces gut inflammation due to T-regulatory response in Muc2 null mice.Feofanova N.A., Bets V.D., Borisova M.A., Litvinova E.A.View abstractCategoriesFunctionSourceMGI: 1339364PubMedEurope PMCPLoS One 17:e0278714-e0278714 (2022)Mapped to8
Maf family transcription factors are required for nutrient uptake in the mouse neonatal gut.Bara A.M., Chen L., Ma C., Underwood J., Moreci R.S., Sumigray K., Sun T., Diao Y., Verzi M., Lechler T.View abstractCategoriesFunctionSourceMGI: 1339364PubMedEurope PMCDevelopment 149:dev201251-dev201251 (2022)Mapped to52
Deletion of TNF in Winnie-<i>APC<sup>Min/+</sup></i> Mice Reveals Its Dual Role in the Onset and Progression of Colitis-Associated Colorectal Cancer.Verna G., Liso M., Cavalcanti E., Armentano R., Miraglia A., Monsurro V., Chieppa M., De Santis S.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1339364PubMedEurope PMCInt J Mol Sci 23:15145-15145 (2022)Mapped to25
Maternal exercise improves epithelial development of fetal intestine by enhancing apelin signaling and oxidative metabolism.Chae S.A., Son J.S., de Avila J.M., Du M., Zhu M.J.View abstractCategoriesFunction, ExpressionSourceMGI: 1339364PubMedEurope PMCAm J Physiol Regul Integr Comp Physiol 323:R728-R738 (2022)Mapped to92
Colitis-associated intestinal microbiota regulates brain glycine and host behavior in mice.Morozova M.V., Borisova M.A., Snytnikova O.A., Achasova K.M., Litvinova E.A., Tsentalovich Y.P., Kozhevnikova E.N.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1339364PubMedEurope PMCSci Rep 12:16345-16345 (2022)Mapped to7
Mesenchymal-epithelial interaction regulates gastrointestinal tract development in mouse embryos.Zhao L., Song W., Chen Y.G.View abstractCategoriesFunction, ExpressionSourceMGI: 1339364PubMedEurope PMCCell Rep 40:111053-111053 (2022)Mapped to42
Nrf2 Transcriptional Activity Governs Intestine Development.Kopacz A., Kloska D., Klimczyk D., Kopec M., Jozkowicz A., Piechota-Polanczyk A.View abstractCategoriesFunction, ExpressionSourceMGI: 1339364PubMedEurope PMCInt J Mol Sci 23:6175-6175 (2022)Mapped to16
Role of Mucin 2 Glycoprotein and L-Fucose in Interaction of Immunity and Microbiome within the Experimental Model of Inflammatory Bowel Disease.Bets V.D., Achasova K.M., Borisova M.A., Kozhevnikova E.N., Litvinova E.A.View abstractAnnotationRole of Mucin 2 Glycoprotein and L-Fucose in Interaction of Immunity and Microbiome within the Experimental Model of Inflammatory Bowel Disease.CategoriesFunction, Phenotypes & VariantsSourceGeneRif: 17831PubMedEurope PMCBiochemistry (Mosc) 87:301-318 (2022)Mapped to9