Q80WF7 · Q80WF7_MOUSE
- ProteinABC-type antigen peptide transporter
- GeneTap2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids702 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Catalytic activity
- a peptide antigen(in) + ATP + H2O = a peptide antigen(out) + ADP + H+ + phosphateThis reaction proceeds in the forward direction.
a peptide antigen RHEA-COMP:16941 + CHEBI:30616 + CHEBI:15377 = a peptide antigen RHEA-COMP:16941 + CHEBI:456216 + CHEBI:15378 + CHEBI:43474
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | TAP complex | |
Molecular Function | ABC-type peptide transporter activity | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | MHC protein binding | |
Molecular Function | tapasin binding | |
Biological Process | adaptive immune response | |
Biological Process | antigen processing and presentation of endogenous peptide antigen via MHC class I |
Keywords
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameABC-type antigen peptide transporter
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionQ80WF7
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 58-79 | Helical | ||||
Sequence: LLGLVGTLLPLLCLATPLFFSL | ||||||
Transmembrane | 99-119 | Helical | ||||
Sequence: WGWLLAGYGAVALSWAVWAVL | ||||||
Transmembrane | 148-168 | Helical | ||||
Sequence: LPFLIAAFFFLVVAVWGETLI | ||||||
Transmembrane | 188-215 | Helical | ||||
Sequence: FASAIFFMCLFSVGSSFSAGCRGGSFLF | ||||||
Transmembrane | 269-287 | Helical | ||||
Sequence: ILLRSLVKVVGLYFFMLQV |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-28 | |||||
Sequence: MALSYLRPWVSLLLADMALLGLLQGSLG | ||||||
Chain | PRO_5014311937 | 29-702 | ABC-type antigen peptide transporter | |||
Sequence: NLLPQGLPGLWIEGTLRLGVLWGLLKVGELLGLVGTLLPLLCLATPLFFSLRALVGGTASTSVVRVASASWGWLLAGYGAVALSWAVWAVLSPAGVQEKEPGQENRTLMKRLLKLSRPDLPFLIAAFFFLVVAVWGETLIPRYSGRVIDILGGDFDPDAFASAIFFMCLFSVGSSFSAGCRGGSFLFTMSRINLRIREQLFSSLLRQDLGFFQETKTGELNSRLSSDTSLMSRWLPFNANILLRSLVKVVGLYFFMLQVSPRLTFLSLLDLPLTIAAEKVYNPRHQAVLKEIQDAVAKAGQVVREAVGGLQTVRSFGAEEQEVSRYKEALERCRQLWWRRDLEKDVYLVIRRVMALGMQVLILNCGVQQILAGEVTRGGLLSFLLYQEEVGQYVRNLVYMYGDMLSNVGAAEKVFSYLDRKPNLPQPGILAPPWLEGRVEFQDVSFSYPRRPEKPVLQGLTFTLHPGTVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGEPLTEYDHHYLHRQVVLVGQEPVLFSGSVKDNIAYGLRDCEDAQVMAAAQAACADDFIGEMTNGINTEIGEKGGQLAVGQKQRLAIARALVRNPRVLILDEATSALDAQCEQALQNWRSQGDRTMLVIAHRLHTVQNADQVLVLKQGRLVEHDQLRDGQDVYAHLVQQRLEA |
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 152-434 | ABC transmembrane type-1 | ||||
Sequence: IAAFFFLVVAVWGETLIPRYSGRVIDILGGDFDPDAFASAIFFMCLFSVGSSFSAGCRGGSFLFTMSRINLRIREQLFSSLLRQDLGFFQETKTGELNSRLSSDTSLMSRWLPFNANILLRSLVKVVGLYFFMLQVSPRLTFLSLLDLPLTIAAEKVYNPRHQAVLKEIQDAVAKAGQVVREAVGGLQTVRSFGAEEQEVSRYKEALERCRQLWWRRDLEKDVYLVIRRVMALGMQVLILNCGVQQILAGEVTRGGLLSFLLYQEEVGQYVRNLVYMYGDMLS | ||||||
Domain | 467-701 | ABC transporter | ||||
Sequence: VEFQDVSFSYPRRPEKPVLQGLTFTLHPGTVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGEPLTEYDHHYLHRQVVLVGQEPVLFSGSVKDNIAYGLRDCEDAQVMAAAQAACADDFIGEMTNGINTEIGEKGGQLAVGQKQRLAIARALVRNPRVLILDEATSALDAQCEQALQNWRSQGDRTMLVIAHRLHTVQNADQVLVLKQGRLVEHDQLRDGQDVYAHLVQQRLE |
Sequence similarities
Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length702
- Mass (Da)77,464
- Last updated2004-03-01 v2
- Checksum1EC4E90FCF890C54