Q802E5 · Q802E5_CHICK

Function

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Note: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

Features

Showing features for active site, binding site.

1736100200300400500600700
Type
IDPosition(s)Description
Active site538Proton donor
Binding site542Zn2+ 1 (UniProtKB | ChEBI)
Binding site578Zn2+ 1 (UniProtKB | ChEBI)
Binding site579Zn2+ 2 (UniProtKB | ChEBI)
Binding site579Zn2+ 1 (UniProtKB | ChEBI)
Binding site699Zn2+ 1 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Function3',5'-cyclic-nucleotide phosphodiesterase activity
Molecular Functionmetal ion binding
Biological Processsignal transduction

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphodiesterase
  • EC number

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Galloanserae > Galliformes > Phasianidae > Phasianinae > Gallus

Accessions

  • Primary accession
    Q802E5

Organism-specific databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain462-736PDEase

Sequence similarities

Belongs to the cyclic nucleotide phosphodiesterase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    736
  • Mass (Da)
    85,136
  • Last updated
    2003-06-01 v1
  • Checksum
    49025DE85F06DD4D
MSISEDDVEKFLDGNPAFAKQYFEKKLKTESCDDNESEILFELIQDMQESINMEKVVFKTLRRIRSLIHADRCSLFMYRQRNGTPELATRLFNIQEGSTLEECLVSPDCEIVYPLDLGIVGYVAQTKKTMNIKDVSECPQFSSFVDELTDYTTKSILATPILNGKDLVAVILAINKLNGPFFTNSDETLFLKYLNFASLNLKIYHLSYLHNCETRRGQVLLWSANKVFEELTDIERQFHKAFYTVRAYLNCDRYSVGLLDMTKQKEFFDLWPVLLGEVPPYSGPRTPDGREIVFYKVIDYILHGKEDIKVIPNPTPDHWALVTGLPTYVAESGFICNIMNAAADEMFNFQEGPLDESGWTIKNVLSMPIVNKKEEIVGVVTFFNRKDGKPFDEQDETLMESLTQFLGWSVLNTDTYDKMNKLENRKDIAQDMVLYHVKCDKDEIQEILPTREKLGKEPSECEEEELASILKEQLPGPTKFEIYEFRFSDFDCTELELVKCGIQMYYELGVVKKFQIPQEVLVRFVYSVSKGYRKITYHNWRHGFNVAQTMFTLLMTGKLKRYYTDLEAFAMVTAALCHDIDHRGTNNLYQMKSQNPLAKLHGSSILERHHLDFGKFLLSEESLNICQNLNRRQHEHMIHLMDIAIIATDLALYFKKRTMFQKIVDESKTYDNTTAWTDYLSLETTKKEVVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLEISVLQQQP

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue736

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY226460
EMBL· GenBank· DDBJ
AAO67732.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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