Q7ZVE6 · PLGT2_DANRE

Function

function

Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C. Can also catalyze the transfer of xylose from UDP-xylose but less efficiently.

Catalytic activity

Pathway

Protein modification; protein glycosylation.

GO annotations

AspectTerm
Cellular Componentendomembrane system
Cellular Componentendoplasmic reticulum lumen
Molecular FunctionEGF-domain serine glucosyltransferase activity
Molecular FunctionEGF-domain serine xylosyltransferase activity
Molecular Functionglucosyltransferase activity
Molecular FunctionUDP-glucosyltransferase activity
Molecular FunctionUDP-xylosyltransferase activity
Biological Processnervous system development
Biological Processprotein O-linked glycosylation via serine

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein O-glucosyltransferase 2
  • EC number
  • Alternative names
    • KDEL motif-containing protein 1
    • Protein O-xylosyltransferase POGLUT2
      (EC:2.4.2.-
      ) . EC:2.4.2.- (UniProtKB | ENZYME | Rhea)

Gene names

    • Name
      poglut2
    • Synonyms
      kdelc1
    • ORF names
      si:dkey-22a1.1, zgc:56065

Organism names

  • Taxonomic identifier
  • Strains
    • Tuebingen
    • AB
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    Q7ZVE6
  • Secondary accessions
    • B0CM11
    • Q5RI39

Proteomes

    • Identifier
    • Component
      Alternate scaffold 9, Chromosome 9

Organism-specific databases

Subcellular Location

PTM/Processing

Features

Showing features for signal, chain, glycosylation.

Type
IDPosition(s)Description
Signal1-22
ChainPRO_000024716523-500Protein O-glucosyltransferase 2
Glycosylation60N-linked (GlcNAc...) asparagine
Glycosylation259N-linked (GlcNAc...) asparagine

Keywords

Proteomic databases

PTM databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for repeat, motif.

Type
IDPosition(s)Description
Repeat23-128Filamin
Motif497-500Prevents secretion from ER

Sequence similarities

Belongs to the KDELC family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    500
  • Mass (Da)
    57,802
  • Last updated
    2003-06-01 v1
  • Checksum
    AD1C93F7F5A8D23E
MLRKLLLLLMSCIIFLTRRSKAAAAASASKTLVWGPGLETNAVLPARFFFIQTVDTTGTNFTTSPGENTFEVKITSPTEPYARIWIQILDRNDGSFLVRYRMYASYTDLHVEVLLKDKLVGKSPYVLRGAVYHESCDCPEPDGALWEKNMHCPASFSQIESDLSIFQSVDPDRNAHEIIQRFGKSHSLCHYTIKNNQVYIKTHGEHVGFRIFMDAFLLSLTRKVKLPDIEFFVNLGDWPLEKRRASQNPSPVFSWCGSNDTRDIVMPTYDLTESVLETMGRVSLDMMSVQGHTGPVWEKKINKGFWRGRDSRKERLELVKLARANTAMLDAALTNFFFFKHDESLYGPLVKHVSFFDFFKYKYQINVDGTVAAYRLPYLLAGDSVVFKHDSIYYEHFYNELQPWVHYIPFRSDLSDLLEKIQWAKDHDEEAKKIALAGQQFARTHLMGDSVFCYYHKLFQKYAELQVTKPKVRDGMELVEQPKDDLFPCYCARKKVRDEL

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict26in Ref. 1; CAP71956
Sequence conflict69in Ref. 1; CAP71956
Sequence conflict71in Ref. 1; CAP71956
Sequence conflict167in Ref. 1; CAP71956
Sequence conflict178in Ref. 1; CAP71956
Sequence conflict323in Ref. 2; CAI20990
Sequence conflict455in Ref. 1; CAP71956

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CU638807
EMBL· GenBank· DDBJ
CAP71956.1
EMBL· GenBank· DDBJ
mRNA
BX322637
EMBL· GenBank· DDBJ
CAI20990.1
EMBL· GenBank· DDBJ
Genomic DNA
BC045893
EMBL· GenBank· DDBJ
AAH45893.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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