Characterization of long cDNA clones from human adult spleen.Hattori A., Okumura K., Nagase T., Kikuno R., Hirosawa M., Ohara O.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)TissueSpleenCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCDNA Res. 7:357-366 (2000)Cited in19
Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H.[...], Sugano S.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3)TissueSpleenCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Genet. 36:40-45 (2004)Cited in99+99+
The DNA sequence and analysis of human chromosome 6.Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E.[...], Beck S.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 425:805-811 (2003)Cited in99+99+
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).The MGC Project TeamView abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT HIS-32TissueLeukocyte, LymphCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenome Res. 14:2121-2127 (2004)Cited in99+99+
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.View abstractCited forPHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-654, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]TissueLiverCategoriesPTM / Processing, SequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Proteomics 96:253-262 (2014)Cited in99+99+Mapped to2
Activation of RhoA and SAPK/JNK signalling pathways by the RhoA-specific exchange factor mNET1.Alberts A.S., Treisman R.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3000203PubMedEurope PMCEMBO J. 17:4075-4085 (1998)Cited in1Mapped to81
PAK kinases are directly coupled to the PIX family of nucleotide exchange factors.Manser E., Loo T.-H., Koh C.-G., Zhao Z.-S., Chen X.-Q., Tan L., Tan I., Leung T., Lim L.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3000203PubMedEurope PMCMol. Cell 1:183-192 (1998)Cited in1Mapped to79
Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos.Nimnual A.S., Yatsula B.A., Bar-Sagi D.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3000203PubMedEurope PMCScience 279:560-563 (1998)Mapped to66
Rho GTPases and signaling networks.Van Aelst L., D'Souza-Schorey C.AnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3000203PubMedEurope PMCGenes Dev 11:2295-2322 (1997)Mapped to92
Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases.Olson M.F., Pasteris N.G., Gorski J.L., Hall A.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3000203PubMedEurope PMCCurr Biol 6:1628-1633 (1996)Mapped to66
Identification of a novel guanine nucleotide exchange factor for the rho GTPase.Hart M.J., Sharma S., el Masry N., Qiu R.-G., McCabe P., Polakis P., Bollag G.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3000203PubMedEurope PMCJ. Biol. Chem. 271:25452-25458 (1996)Cited in1Mapped to77
The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac- specific and rho-specific guanine nucleotide exchange factor domains.Debant A., Serra-Pages C., Seipel K., O'Brien S., Tang M., Park S.-H., Streuli M.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3000203PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 93:5466-5471 (1996)Cited in1Mapped to77
A role for Rac in Tiam1-induced membrane ruffling and invasion.Michiels F., Habets G.G.M., Stam J.C., van der Kammen R.A., Collard J.G.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3000203PubMedEurope PMCNature 375:338-340 (1995)Cited in1Mapped to77
Direct involvement of the small GTP-binding protein Rho in lbc oncogene function.Zheng Y., Olson M.F., Hall A., Cerione R.A., Toksoz D.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3000203PubMedEurope PMCJ Biol Chem 270:9031-9034 (1995)Mapped to96
Abr and Bcr are multifunctional regulators of the Rho GTP-binding protein family.Chuang T.H., Xu X., Kaartinen V., Heisterkamp N., Groffen J., Bokoch G.M.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3000203PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 92:10282-10286 (1995)Cited in2Mapped to99+
Characterization of guanine nucleotide exchange activity of DH domain of human FGD2.Chuan J., He S., Xie T., Wang G., Yang Z.View abstractAnnotationCharacterization of guanine nucleotide exchange activity of DH domain of human FGD2.CategoriesFunction, InteractionSourceGeneRif: 221472PubMedEurope PMCProtein Expr Purif 176:105693-105693 (2020)Mapped to6
Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.Mueller P.M., Rademacher J., Bagshaw R.D., Wortmann C., Barth C., van Unen J., Alp K.M., Giudice G., Eccles R.L.[...], Rocks O.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3000203PubMedEurope PMCNat. Cell Biol. 22:498-511 (2020)Cited in3Mapped to99+
Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms.Bagci H., Sriskandarajah N., Robert A., Boulais J., Elkholi I.E., Tran V., Lin Z.Y., Thibault M.P., Dube N.[...], Cote J.F.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3000203PubMedEurope PMCNat. Cell Biol. 22:120-134 (2020)Cited in2Mapped to99+
Structural Basis for the Dual Substrate Specificity of DOCK7 Guanine Nucleotide Exchange Factor.Kukimoto-Niino M., Tsuda K., Ihara K., Mishima-Tsumagari C., Honda K., Ohsawa N., Shirouzu M.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3000203PubMedEurope PMCStructure 27:741-748.e3 (2019)Mapped to75
A CDC42-centered signaling unit is a dominant positive regulator of endothelial integrity.Amado-Azevedo J., Reinhard N.R., van Bezu J., de Menezes R.X., van Beusechem V.W., van Nieuw Amerongen G.P., van Hinsbergh V.W.M., Hordijk P.L.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3000203PubMedEurope PMCSci Rep 7:10132-10132 (2017)Mapped to99+
Characterization of the activation of small GTPases by their GEFs on membranes using artificial membrane tethering.Peurois F., Veyron S., Ferrandez Y., Ladid I., Benabdi S., Zeghouf M., Peyroche G., Cherfils J.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3000203PubMedEurope PMCBiochem J 474:1259-1272 (2017)Mapped to79
LRCH1 interferes with DOCK8-Cdc42-induced T cell migration and ameliorates experimental autoimmune encephalomyelitis.Xu X., Han L., Zhao G., Xue S., Gao Y., Xiao J., Zhang S., Chen P., Wu Z.Y.[...], Wang H.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3000203PubMedEurope PMCJ. Exp. Med. 214:209-226 (2017)Cited in5Mapped to59
Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions.Martins R., Maier J., Gorki A.D., Huber K.V., Sharif O., Starkl P., Saluzzo S., Quattrone F., Gawish R.[...], Knapp S.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3000203PubMedEurope PMCNat Immunol 17:1361-1372 (2016)Mapped to53
PLEKHG3 enhances polarized cell migration by activating actin filaments at the cell front.Nguyen T.T., Park W.S., Park B.O., Kim C.Y., Oh Y., Kim J.M., Choi H., Kyung T., Kim C.H.[...], Heo W.D.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3000203PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 113:10091-10096 (2016)Cited in1Mapped to67
ARHGEF15 overexpression worsens the prognosis in patients with pancreatic ductal adenocarcinoma through enhancing the motility and proliferative activity of the cancer cells.Fukushima H., Yasumoto M., Ogasawara S., Akiba J., Kitasato Y., Nakayama M., Naito Y., Ishida Y., Okabe Y.[...], Yano H.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3000203PubMedEurope PMCMol Cancer 15:32-32 (2016)Mapped to82