Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP.Nassar N., Hoffman G.R., Manor D., Clardy J.C., Cerione R.A.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-200803PubMedEurope PMCNat Struct Biol 5:1047-1052 (1998)Mapped to48
Regulation of RhoA GTP hydrolysis by the GTPase-activating proteins p190, p50RhoGAP, Bcr, and 3BP-1.Zhang B., Zheng Y.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-200803PubMedEurope PMCBiochemistry 37:5249-5257 (1998)Mapped to48
Characterization of the interactions between the small GTPase Cdc42 and its GTPase-activating proteins and putative effectors. Comparison of kinetic properties of Cdc42 binding to the Cdc42-interactive domains.Zhang B., Wang Z.X., Zheng Y.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-200803PubMedEurope PMCJ Biol Chem 272:21999-22007 (1997)Mapped to48
The atypical Rho GTPase RhoU interacts with intersectin-2 to regulate endosomal recycling pathways.Gubar O., Croise P., Kropyvko S., Gryaznova T., Toth P., Blangy A., Vitale N., Rynditch A., Gasman S., Ory S.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-200803PubMedEurope PMCJ Cell Sci 133:jcs234104-jcs234104 (2020)Mapped to39
Potential Prognostic Predictors and Molecular Targets for Skin Melanoma Screened by Weighted Gene Co-expression Network Analysis.Chen S., Liu Z., Li M., Huang Y., Wang M., Zeng W., Wei W., Zhang C., Gong Y., Guo L.View abstractAnnotationPotential Prognostic Predictors and Molecular Targets for Skin Melanoma Screened by Weighted Gene Co-expression Network Analysis.CategoriesFunction, ExpressionSourceGeneRif: 257106PubMedEurope PMCCurr Gene Ther 20:5-14 (2020)Mapped to15
PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion.Dart A.E., Box G.M., Court W., Gale M.E., Brown J.P., Pinder S.E., Eccles S.A., Wells C.M.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-200803PubMedEurope PMCJ Cell Biol 211:863-879 (2015)Mapped to39
Myosin-IXA regulates collective epithelial cell migration by targeting RhoGAP activity to cell-cell junctions.Omelchenko T., Hall A.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-200803PubMedEurope PMCCurr Biol 22:278-288 (2012)Mapped to50
The transforming Rho family GTPase Wrch-1 disrupts epithelial cell tight junctions and epithelial morphogenesis.Brady D.C., Alan J.K., Madigan J.P., Fanning A.S., Cox A.D.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-200803PubMedEurope PMCMol Cell Biol 29:1035-1049 (2009)Mapped to39
The atypical Rho family GTPase Wrch-1 regulates focal adhesion formation and cell migration.Chuang Y.Y., Valster A., Coniglio S.J., Backer J.M., Symons M.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-200803PubMedEurope PMCJ Cell Sci 120:1927-1934 (2007)Mapped to39
Inactivation of Rho GTPases by p190 RhoGAP reduces human pancreatic cancer cell invasion and metastasis.Kusama T., Mukai M., Endo H., Ishikawa O., Tatsuta M., Nakamura H., Inoue M.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-200803PubMedEurope PMCCancer Sci 97:848-853 (2006)Mapped to50
Atypical mechanism of regulation of the Wrch-1 Rho family small GTPase.Shutes A., Berzat A.C., Cox A.D., Der C.J.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-200803PubMedEurope PMCCurr Biol 14:2052-2056 (2004)Mapped to41
Wrch1 is a GTPase-deficient Cdc42-like protein with unusual binding characteristics and cellular effects.Saras J., Wollberg P., Aspenstrom P.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-200803PubMedEurope PMCExp Cell Res 299:356-369 (2004)Mapped to39
Wrch-1, a novel member of the Rho gene family that is regulated by Wnt- 1.Tao W., Pennica D., Xu L., Kalejta R.F., Levine A.J.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-200803PubMedEurope PMCGenes Dev. 15:1796-1807 (2001)Cited in2Mapped to43