Human cytomegalovirus UL141 promotes efficient downregulation of the natural killer cell activating ligand CD112.
- AnnotationThe authors now show that human cytomegalovirus targets CD112 for proteasome-mediated degradation by 48 h post-infection thus removing both activating ligands for DNAM-1 from the cell surface during productive infection.
- CategoryFunction
- SourceGeneRif: 5819