Q7XUN6 · SIT2_ORYSJ
- ProteinL-type lectin-domain containing receptor kinase SIT2
- GeneSIT2
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids673 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score5/5
Function
function
Lectin-domain containing receptor kinase involved in salt stress response (PubMed:24907341).
Acts as a negative regulator of salt tolerance (PubMed:24907341).
Acts as a negative regulator of salt tolerance (PubMed:24907341).
Miscellaneous
The gain-of-function mutant sit2-D (T-DNA tagging) exhibits reduced tolerance to salt stress.
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]This reaction proceeds in the forward direction.
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | carbohydrate binding | |
Molecular Function | protein serine kinase activity | |
Molecular Function | transmembrane receptor protein serine/threonine kinase activity | |
Biological Process | defense response to bacterium | |
Biological Process | defense response to oomycetes | |
Biological Process | negative regulation of response to salt stress | |
Biological Process | protein phosphorylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameL-type lectin-domain containing receptor kinase SIT2
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Oryzoideae > Oryzeae > Oryzinae > Oryza > Oryza sativa
Accessions
- Primary accessionQ7XUN6
- Secondary accessions
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Single-pass type I membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 28-296 | Extracellular | ||||
Sequence: TDERFVFNGFTGANLSFDGMATVTSNGLLMLTNGTNQLKGHAFFPSPLQFQRGPNSTAMQSFSTAFVIGIIGAFEDLSSHGMAFIIAKSKNLTSALPGQFMGLVNSANNGNATNHLFAVEFDTILNSEFNDMSGNHVGIDVNGLNSVDADNAGYYDDGTGDFKNMSLVSRRPMQVWVDFDGQTMQVNVTMAPLEVARPKKPLLSKIVNISSVIDDTAYVGFSSATGILFCRHYVLGWSFKMNGAAPALNISSLPSLPVTFPKPRSKTLE | ||||||
Transmembrane | 297-317 | Helical | ||||
Sequence: IVLPIASAVLVFAVAAAVFVF | ||||||
Topological domain | 318-673 | Cytoplasmic | ||||
Sequence: MRRRRMFSELKEEWEVTFGPHRFSYKDLFHATDGFSDKRLLGIGGFGRVYRGVLPSSKAEVAVKKVAHGSRQGMREFVAEVVSIGRLRHRNLVQLLGYCRRKGELLLVYDYMPNGSLDKQLYDQGKITLRWAQRFRIIRGVASGLLYLHEDWEQVVVHRDIKASNVLLDADMNGRLGDFGLARLYDHGTDPHTTHVVGTMGYLAPELGHTGKASKASDVFAFGAFMLEVACGRKPVAQDARDNRVVLVDWVLDRWRAGAITDTVDPRLHGDFVESEASLVLRLGLLCSHPLPGARPGTRQLVQYLEGDVPLPELSPTYQSFNMLALMQDQGFDPYVMSYPMTSTSAGTFSDLSGGR |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain, glycosylation.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-27 | |||||
Sequence: MVLPKPEMPFFVLLLFLGLGCLRPAAA | ||||||
Chain | PRO_5010144878 | 28-673 | L-type lectin-domain containing receptor kinase SIT2 | |||
Sequence: TDERFVFNGFTGANLSFDGMATVTSNGLLMLTNGTNQLKGHAFFPSPLQFQRGPNSTAMQSFSTAFVIGIIGAFEDLSSHGMAFIIAKSKNLTSALPGQFMGLVNSANNGNATNHLFAVEFDTILNSEFNDMSGNHVGIDVNGLNSVDADNAGYYDDGTGDFKNMSLVSRRPMQVWVDFDGQTMQVNVTMAPLEVARPKKPLLSKIVNISSVIDDTAYVGFSSATGILFCRHYVLGWSFKMNGAAPALNISSLPSLPVTFPKPRSKTLEIVLPIASAVLVFAVAAAVFVFMRRRRMFSELKEEWEVTFGPHRFSYKDLFHATDGFSDKRLLGIGGFGRVYRGVLPSSKAEVAVKKVAHGSRQGMREFVAEVVSIGRLRHRNLVQLLGYCRRKGELLLVYDYMPNGSLDKQLYDQGKITLRWAQRFRIIRGVASGLLYLHEDWEQVVVHRDIKASNVLLDADMNGRLGDFGLARLYDHGTDPHTTHVVGTMGYLAPELGHTGKASKASDVFAFGAFMLEVACGRKPVAQDARDNRVVLVDWVLDRWRAGAITDTVDPRLHGDFVESEASLVLRLGLLCSHPLPGARPGTRQLVQYLEGDVPLPELSPTYQSFNMLALMQDQGFDPYVMSYPMTSTSAGTFSDLSGGR | ||||||
Glycosylation | 41 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 60 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 82 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 118 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 138 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 191 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 214 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 235 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 276 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N |
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Tissue specificity
Mainly expressed in root epidermal cells.
Induction
Induced by salt stress.
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 32-270 | Legume-lectin like | ||||
Sequence: FVFNGFTGANLSFDGMATVTSNGLLMLTNGTNQLKGHAFFPSPLQFQRGPNSTAMQSFSTAFVIGIIGAFEDLSSHGMAFIIAKSKNLTSALPGQFMGLVNSANNGNATNHLFAVEFDTILNSEFNDMSGNHVGIDVNGLNSVDADNAGYYDDGTGDFKNMSLVSRRPMQVWVDFDGQTMQVNVTMAPLEVARPKKPLLSKIVNISSVIDDTAYVGFSSATGILFCRHYVLGWSFKMNG | ||||||
Domain | 352-631 | Protein kinase | ||||
Sequence: FSDKRLLGIGGFGRVYRGVLPSSKAEVAVKKVAHGSRQGMREFVAEVVSIGRLRHRNLVQLLGYCRRKGELLLVYDYMPNGSLDKQLYDQGKITLRWAQRFRIIRGVASGLLYLHEDWEQVVVHRDIKASNVLLDADMNGRLGDFGLARLYDHGTDPHTTHVVGTMGYLAPELGHTGKASKASDVFAFGAFMLEVACGRKPVAQDARDNRVVLVDWVLDRWRAGAITDTVDPRLHGDFVESEASLVLRLGLLCSHPLPGARPGTRQLVQYLEGDVPLPEL |
Sequence similarities
In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
In the N-terminal section; belongs to the leguminous lectin family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length673
- Mass (Da)73,872
- Last updated2004-03-01 v2
- ChecksumB102E5D74EAAD233
Sequence caution
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AL662984 EMBL· GenBank· DDBJ | CAD41144.2 EMBL· GenBank· DDBJ | Genomic DNA | ||
AP008210 EMBL· GenBank· DDBJ | BAF15310.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
AP014960 EMBL· GenBank· DDBJ | BAS90216.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
CM000141 EMBL· GenBank· DDBJ | EEE61393.1 EMBL· GenBank· DDBJ | Genomic DNA |