Q7V2F8 · PYRH_PROMP
- ProteinUridylate kinase
- GenepyrH
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids234 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reversible phosphorylation of UMP to UDP.
Catalytic activity
- UMP + ATP = UDP + ADP
Activity regulation
Inhibited by UTP.
Pathway
Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 9-12 | ATP (UniProtKB | ChEBI) | |||
Binding site | 51 | UMP (UniProtKB | ChEBI) | |||
Binding site | 52 | ATP (UniProtKB | ChEBI) | |||
Binding site | 56 | ATP (UniProtKB | ChEBI) | |||
Binding site | 71 | UMP (UniProtKB | ChEBI) | |||
Binding site | 132-139 | UMP (UniProtKB | ChEBI) | |||
Binding site | 159 | ATP (UniProtKB | ChEBI) | |||
Binding site | 165 | ATP (UniProtKB | ChEBI) | |||
Binding site | 168 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | UMP kinase activity | |
Biological Process | 'de novo' CTP biosynthetic process | |
Biological Process | phosphorylation | |
Biological Process | UDP biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUridylate kinase
- EC number
- Short namesUK
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Cyanobacteriota > Cyanophyceae > Synechococcales > Prochlorococcaceae > Prochlorococcus
Accessions
- Primary accessionQ7V2F8
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000323926 | 1-234 | Uridylate kinase | ||
Interaction
Structure
Sequence
- Sequence statusComplete
- Length234
- Mass (Da)25,356
- Last updated2003-10-01 v1
- MD5 Checksum01C741FE5F130B57F5A6E6F9354AAF16
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BX548174 EMBL· GenBank· DDBJ | CAE18981.1 EMBL· GenBank· DDBJ | Genomic DNA |