Q7V2F8 · PYRH_PROMP

Function

function

Catalyzes the reversible phosphorylation of UMP to UDP.

Catalytic activity

Activity regulation

Inhibited by UTP.

Pathway

Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.

Features

Showing features for binding site.

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TypeIDPosition(s)Description
Binding site9-12ATP (UniProtKB | ChEBI)
Binding site51UMP (UniProtKB | ChEBI)
Binding site52ATP (UniProtKB | ChEBI)
Binding site56ATP (UniProtKB | ChEBI)
Binding site71UMP (UniProtKB | ChEBI)
Binding site132-139UMP (UniProtKB | ChEBI)
Binding site159ATP (UniProtKB | ChEBI)
Binding site165ATP (UniProtKB | ChEBI)
Binding site168ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionUMP kinase activity
Biological Process'de novo' CTP biosynthetic process
Biological Processphosphorylation
Biological ProcessUDP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Uridylate kinase
  • EC number
  • Short names
    UK
  • Alternative names
    • Uridine monophosphate kinase
      (UMP kinase
      ; UMPK
      )

Gene names

    • Name
      pyrH
    • Synonyms
      smbA
    • Ordered locus names
      PMM0522

Organism names

Accessions

  • Primary accession
    Q7V2F8

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003239261-234Uridylate kinase

Interaction

Subunit

Homohexamer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the UMP kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    234
  • Mass (Da)
    25,356
  • Last updated
    2003-10-01 v1
  • MD5 Checksum
    01C741FE5F130B57F5A6E6F9354AAF16
MTYKRVLLKLSGEALMGDKPYGIDPAIVQSIAEDVERVIANKVQLAIVVGGGNIFRGLKGSADGMDRATADYVGMLATVMNAISLQDGLERVGVETRVQTAIEMQEIAEPYIRRRAMRHLEKGRVVVFGGGCGNPFFTTDTTAALRAAEINAEVVMKATKVDGVYDRDPNKFKEAKKYSSLTYQQVLSDEIAVMDSTAIALCKDNNIPIMVFDIFKKGNISRAVAGESIGSLIS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX548174
EMBL· GenBank· DDBJ
CAE18981.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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