Q7V2A0 · DCUP_PROMP

Function

function

Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.

Catalytic activity

Pathway

Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.

Features

Showing features for binding site, site.

134650100150200250300
Type
IDPosition(s)Description
Binding site26-30substrate
Binding site45substrate
Binding site76substrate
Site76Transition state stabilizer
Binding site153substrate
Binding site208substrate
Binding site323substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionuroporphyrinogen decarboxylase activity
Biological Processprotoporphyrinogen IX biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Uroporphyrinogen decarboxylase
  • EC number
  • Short names
    UPD
    ; URO-D

Gene names

    • Name
      hemE
    • Ordered locus names
      PMM0583

Organism names

Accessions

  • Primary accession
    Q7V2A0

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001876251-346Uroporphyrinogen decarboxylase

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the uroporphyrinogen decarboxylase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    346
  • Mass (Da)
    38,974
  • Last updated
    2003-10-01 v1
  • MD5 Checksum
    42AD1E7C8894657872EAA5E373EBA5F7
MGENLPLLLSAALGKKVNRPPVWMMRQAGRYMKIYRDLRERYPSFRERSENPELSYEISMQPFLAFKPDGVILFSDILTPLPGMGINFEIIESKGPIIEDPIRNIRQVEKLKELIPNESLSFVGEVLSSLKKDVKNEATVLGFVGAPWTLAAYVVEGKSSKNYSLIKSMAFKEPDLLHKLLDHFAKSIGEYLKYQIKSGAQVVQIFDSWAGQLSPQDYDIFAGPYQKKVVDIVKEEFPDTPIILYISGSAGVLERMAKTGVDIISLDWTVDIEEACKRIPTGIGIQGNVDPGILFGNKDSIKERIDNTFNKVKERKYILNLGHGILPGTPEENAKTFFEHGKKLTY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX548174
EMBL· GenBank· DDBJ
CAE19042.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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