Q7V2A0 · DCUP_PROMP
- ProteinUroporphyrinogen decarboxylase
- GenehemE
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids346 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
Catalytic activity
- uroporphyrinogen III + 4 H+ = coproporphyrinogen III + 4 CO2
Pathway
Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.
Features
Showing features for binding site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 26-30 | substrate | |||
Binding site | 45 | substrate | |||
Binding site | 76 | substrate | |||
Site | 76 | Transition state stabilizer | |||
Binding site | 153 | substrate | |||
Binding site | 208 | substrate | |||
Binding site | 323 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | uroporphyrinogen decarboxylase activity | |
Biological Process | protoporphyrinogen IX biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUroporphyrinogen decarboxylase
- EC number
- Short namesUPD ; URO-D
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Cyanobacteriota > Cyanophyceae > Synechococcales > Prochlorococcaceae > Prochlorococcus
Accessions
- Primary accessionQ7V2A0
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000187625 | 1-346 | Uroporphyrinogen decarboxylase | ||
Interaction
Structure
Sequence
- Sequence statusComplete
- Length346
- Mass (Da)38,974
- Last updated2003-10-01 v1
- MD5 Checksum42AD1E7C8894657872EAA5E373EBA5F7
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BX548174 EMBL· GenBank· DDBJ | CAE19042.1 EMBL· GenBank· DDBJ | Genomic DNA |