Q7UG04 · MTXAW_RHOBA

Function

function

Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; O-acetyl-L-homoserine from L-homoserine: step 1/1.

Features

Showing features for active site, binding site.

162350100150200250300350400450500550600
TypeIDPosition(s)Description
Active site183Nucleophile
Binding site253substrate
Active site348
Active site381
Binding site382substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionhomoserine O-acetyltransferase activity
Biological Processhomoserine metabolic process
Biological Processmethionine biosynthetic process

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Bifunctional methionine biosynthesis protein MetXA/MetW

Including 2 domains:

  • Recommended name
    Homoserine O-acetyltransferase
  • EC number
  • Short names
    HAT
  • Alternative names
    • Homoserine transacetylase
      (HTA
      )
  • Recommended name
    Protein MetW

Gene names

    • Name
      metXA
    • Synonyms
      metX
    • Ordered locus names
      RB8222

Organism names

Accessions

  • Primary accession
    Q7UG04

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004403061-623Bifunctional methionine biosynthesis protein MetXA/MetW

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias1-25Polar residues
Region1-30Disordered
Domain77-385AB hydrolase-1
Region417-619MetW

Sequence similarities

In the N-terminal section; belongs to the AB hydrolase superfamily. MetX family.
In the C-terminal section; belongs to the MetW family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    623
  • Mass (Da)
    68,950
  • Last updated
    2003-10-01 v1
  • Checksum
    445E62055967CCF5
MTSGRSTRVTMFESQASMGEPSNEDLSSTDDVRTDAPLAYAKYVTFDQSLPLERGGELPEIRCCYETWGTLNDDGSNAVLVCHAVSGDSHAARHDEDDQPGWWDGLIGPGLPIDTDRLFVVCPNVLGGCRGSTGPGDADPTSPDGKPYGANFPRITIGDIVEAQKLLADHLGIRQWRAVVGGSLGGHQVLQWINRYPDAAKTCVAIATSPRLNSQALGFDVIARNAIQTDPHYAGGQYYDKDQRPDTGLAIARMLGHITYLSVEAMEAKFDPDRHDPRQIASQFEQRFSIGSYLAHQGQKFTTRFDANSYVTLSMAMDLFDLGGTRLKLMETFDEATCDFLLISFSSDWLFPPAQSREIVNALTALDKRVTYAEITTNAGHDAFLIAKDIATYGPLIRERLRDTETHPAVPSDITLNVDEESILEIIPAGSSVLDLGCGNGQLLAAIRDRHRTPGPPTTEHRLMGVEVAQENLLATAMRGIDVIDYDLNHGLPAFIDDQFDYVILNATLQAVENVVELLNEMLRVGRHAIISFPNFAYRQLRDHYVTHGRSPKAPGEFDFDWHNTPNRRFPTIADVRDLLGQLNVVIDEEVFWDVDQGQRIEPDNDPNLNADTAVIAFHRENR

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-25Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX294147
EMBL· GenBank· DDBJ
CAD78525.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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