Q7TQA5 · T2R39_MOUSE
- ProteinTaste receptor type 2 member 39
- GeneTas2r39
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids319 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Putative taste receptor which may play a role in the perception of bitterness.
Miscellaneous
Several bitter taste receptors are expressed in a single taste receptor cell.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | bitter taste receptor activity | |
Molecular Function | G protein-coupled receptor activity | |
Molecular Function | taste receptor activity | |
Biological Process | detection of chemical stimulus involved in sensory perception of bitter taste |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTaste receptor type 2 member 39
- Short namesT2R39; mT2R34
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionQ7TQA5
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 1-16 | Extracellular | ||||
Sequence: MAQPSNYWKQDVLPLS | ||||||
Transmembrane | 17-37 | Helical; Name=1 | ||||
Sequence: ILMLTLVATECTIGIIASGIV | ||||||
Topological domain | 38-65 | Cytoplasmic | ||||
Sequence: MAVNAVSWVQKKAISITTRILLLLSVSR | ||||||
Transmembrane | 66-86 | Helical; Name=2 | ||||
Sequence: IGLQSIMLIEITSSIFNVAFY | ||||||
Topological domain | 87-97 | Extracellular | ||||
Sequence: NSVLYRVSNVS | ||||||
Transmembrane | 98-118 | Helical; Name=3 | ||||
Sequence: FVFLNYCSLWFAALLSFFHFV | ||||||
Topological domain | 119-137 | Cytoplasmic | ||||
Sequence: KIANFSYPLFFKLKWRISE | ||||||
Transmembrane | 138-158 | Helical; Name=4 | ||||
Sequence: LMPWLLWLSVFISFSSSMFFS | ||||||
Topological domain | 159-194 | Extracellular | ||||
Sequence: KHKFTVNNNNSLSNNICNFTMKLYVVETNVVNVSFL | ||||||
Transmembrane | 195-215 | Helical; Name=5 | ||||
Sequence: FISGILPPLTMFVATATLLIF | ||||||
Topological domain | 216-247 | Cytoplasmic | ||||
Sequence: SLRRHTLNMRNSATGSRNPCIEAHMQAIKETS | ||||||
Transmembrane | 248-268 | Helical; Name=6 | ||||
Sequence: CFLFLYILNAAALLLSTSNIV | ||||||
Topological domain | 269-273 | Extracellular | ||||
Sequence: DASLF | ||||||
Transmembrane | 274-294 | Helical; Name=7 | ||||
Sequence: WSIVIRIVLPVYPAGHSVLLI | ||||||
Topological domain | 295-319 | Cytoplasmic | ||||
Sequence: QNNPGLRRTWKHLQSQIHLYLQNRF |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain, glycosylation.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000082286 | 1-319 | Taste receptor type 2 member 39 | |||
Sequence: MAQPSNYWKQDVLPLSILMLTLVATECTIGIIASGIVMAVNAVSWVQKKAISITTRILLLLSVSRIGLQSIMLIEITSSIFNVAFYNSVLYRVSNVSFVFLNYCSLWFAALLSFFHFVKIANFSYPLFFKLKWRISELMPWLLWLSVFISFSSSMFFSKHKFTVNNNNSLSNNICNFTMKLYVVETNVVNVSFLFISGILPPLTMFVATATLLIFSLRRHTLNMRNSATGSRNPCIEAHMQAIKETSCFLFLYILNAAALLLSTSNIVDASLFWSIVIRIVLPVYPAGHSVLLIQNNPGLRRTWKHLQSQIHLYLQNRF | ||||||
Glycosylation | 95 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 167 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 176 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 190 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N |
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Gene expression databases
Structure
Sequence
- Sequence statusComplete
- Length319
- Mass (Da)36,308
- Last updated2003-10-01 v1
- Checksum4D29965B184242D0
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AF532790 EMBL· GenBank· DDBJ | AAP40340.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AC157218 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
BK001094 EMBL· GenBank· DDBJ | DAA01233.1 EMBL· GenBank· DDBJ | Genomic DNA |