The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).The MGC Project TeamView abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]StrainFVB/NTissueMammary tumor. C3CategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCGenome Res. 14:2121-2127 (2004)Cited in99+99+
Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain.Hsu W., Zeng L., Costantini F.View abstractCategoriesInteractionSourceMGI: 1096327PubMedEurope PMCJ. Biol. Chem. 274:3439-3445 (1999)Cited in3Mapped to11
Mechanisms of Wnt signaling in development.Wodarz A., Nusse R.View abstractSourceMGI: 1096327PubMedEurope PMCAnnu Rev Cell Dev Biol 14:59-88 (1998)Mapped to33
Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta.Hart M.J., de los Santos R., Albert I.N., Rubinfeld B., Polakis P.View abstractCategoriesFunction, InteractionSourceMGI: 1096327PubMedEurope PMCCurr Biol 8:573-581 (1998)Mapped to63
Two dominant mutations in the mouse fused gene are the result of transposon insertions.Vasicek T.J., Zeng L., Guan X.J., Zhang T., Costantini F., Tilghman S.M.View abstractCategoriesSequences, Phenotypes & VariantsSourceMGI: 1096327PubMedEurope PMCGenetics 147:777-786 (1997)Mapped to6
Derivation of mutant t-haplotypes of the mouse by presumed duplication or deletion.Lyon M.F., Bechtol K.B.CategoriesFunction, SequencesSourceMGI: 1096327PubMedEurope PMCGenet Res 30:63-76 (1977)Mapped to13
The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation.Zeng L., Fagotto F., Zhang T., Hsu W., Vasicek T.J., Perry W.L. III, Lee J.J., Tilghman S.M., Gumbiner B.M., Costantini F.View abstractCategoriesSequencesSourceMGI: 1096327PubMedEurope PMCCell 90:181-192 (1997)Cited in3Mapped to16
Phenotypic and molecular analysis of a transgenic insertional allele of the mouse Fused locus.Perry W.L., Vasicek T.J., Lee J.J., Rossi J.M., Zeng L., Zhang T., Tilghman S.M., Costantini F.View abstractCategoriesSequencesSourceMGI: 1096327PubMedEurope PMCGenetics 141:321-332 (1995)Mapped to6
[Analysis of chimeric mice bearing the fused mutation].Redina O.E., Zhelezova A.I., Golubitsa A.N., Agul'nik A.I., Ruvinskii A.O.View abstractCategoriesSequences, Phenotypes & VariantsSourceMGI: 1096327PubMedEurope PMCGenetika 29:1320-1327 (1993)Mapped to6
Phenotypic expression of the fused (Fu) gene in chimaeric mice.Redina O.E., Zhelezova A.I., Golubitsa A.N., Agulnik A.I., Ruvinsky A.O.View abstractCategoriesSequencesSourceMGI: 1096327PubMedEurope PMCGenet Res 63:183-187 (1994)Mapped to6
High-resolution genetic analysis of a deletion on mouse chromosome 17 extending over the fused, tufted, and homeobox Nkx2-5 loci.Himmelbauer H., Harvey R.P., Copeland N.G., Jenkins N.A., Silver L.M.CategoriesSequencesSourceMGI: 1096327PubMedEurope PMCMamm Genome 5:814-816 (1994)Mapped to29
Genetic map of the fused locus on mouse chromosome 17.Rossi J.M., Chen H., Tilghman S.M.View abstractCategoriesSequencesSourceMGI: 1096327PubMedEurope PMCGenomics 23:178-184 (1994)Mapped to14
Mapping around the Fused locus on mouse chromosome 17.Sutherland H.F., Pick E., Francis F., Lehrach H., Frischauf A.M.View abstractCategoriesSequencesSourceMGI: 1096327PubMedEurope PMCMamm Genome 6:449-453 (1995)Mapped to6
Inheritance of alternative states of the fused gene in mice.Belyaev D.K., Ruvinsky A.O., Borodin P.M.View abstractCategoriesSequences, Phenotypes & VariantsSourceMGI: 1096327PubMedEurope PMCJ Hered 72:107-112 (1981)Mapped to9
H-2 haplotypes, genes, and antigens: second listing. I. Non-H-2 loci on chromosome 17.Klein J., Figueroa F., Klein D.CategoriesSequencesSourceMGI: 1096327PubMedEurope PMCImmunogenetics 16:285-317 (1982)Mapped to66
Knobbly, a new dominant mutation in the mouse that affects embryonic ectoderm organization.Jacobs-Cohen R.J., Spiegelman M., Cookingham J.C., Bennett D.CategoriesSequencesSourceMGI: 1096327PubMedEurope PMCGenet Res 43:43-50 (1984)Mapped to6
The probable mode of gene action in the circling mutants of the mouse.Deol M.S.CategoriesFunctionSourceMGI: 1096327PubMedEurope PMCGenet Res 7:363-371 (1966)Mapped to6
Thin fur, a recessive mutant on chromosome 17 of the mouse.Key M., Hollander W.F.CategoriesSequencesSourceMGI: 1096327PubMedEurope PMCJ Hered 63:97-98 (1972)Mapped to10
TRAF2 decrease promotes the TGF-beta-mTORC1 signal in MAFLD-HCC through enhancing AXIN1-mediated Smad7 degradation.Li Z., Zhao J., Wu Y., Fan S., Yuan H., Xia J., Hu L., Yang J., Liu J.[...], Yang L.View abstractAnnotationTRAF2 decrease promotes the TGF-beta-mTORC1 signal in MAFLD-HCC through enhancing AXIN1-mediated Smad7 degradation.CategoriesFunctionSourceGeneRif: 12005PubMedEurope PMCFASEB J 38:e23491-e23491 (2024)Mapped to10
RSK2 inactivation cooperates with AXIN1 inactivation or beta-catenin activation to promote hepatocarcinogenesis.Schaeffer S., Gupta B., Calatayud A.L., Calderaro J., Caruso S., Hirsch T.Z., Pelletier L., Zucman-Rossi J., Rebouissou S.View abstractAnnotationRSK2 inactivation cooperates with AXIN1 inactivation or beta-catenin activation to promote hepatocarcinogenesis.CategoriesFunctionSourceGeneRif: 12005PubMedEurope PMCJ Hepatol 79:704-716 (2023)Mapped to35
Specific deletion of pii>Axin1pi/i> leads to activation of beta- catenin/BMP signaling resulting in fibular hemimelia phenotype in mice.Xie R., Yi D., Zeng D., Jie Q., Kang Q., Zhang Z., Zhang Z., Xiao G., Chen L.[...], Chen D.View abstractAnnotationSpecific deletion of Axin1 leads to activation of beta-catenin/BMP signaling resulting in fibular hemimelia phenotype in mice.CategoriesFunction, Phenotypes & VariantsSourceGeneRif: 12005, MGI: 1096327PubMedEurope PMCElife 11:e80013-e80013 (2022)Mapped to6
Axin1 Protects Colon Carcinogenesis by an Immune-Mediated Effect.Sanson R., Lazzara S.L., Cune D., Pitasi C.L., Trentesaux C., Fraudeau M., Letourneur F., Saintpierre B., Le Gall M.[...], Perret C.View abstractAnnotationAxin1 Protects Colon Carcinogenesis by an Immune-Mediated Effect.CategoriesFunction, Phenotypes & VariantsSourceGeneRif: 12005PubMedEurope PMCCell Mol Gastroenterol Hepatol 15:689-715 (2023)Mapped to5
Axin1: A novel scaffold protein joins the antiviral network of interferon.Guo Y., Bamunuarachchi G., Vaddadi K., Zhu Z., Gandikota C., Ahmed K., Pushparaj S., More S., Xiao X.[...], Liu L.View abstractAnnotationAxin1: A novel scaffold protein joins the antiviral network of interferon.CategoriesFunctionSourceGeneRif: 12005PubMedEurope PMCMol Microbiol 118:731-743 (2022)Mapped to11
The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK.Zhang C.S., Li M., Wang Y., Li X., Zong Y., Long S., Zhang M., Feng J.W., Wei X.[...], Lin S.C.View abstractCategoriesFunctionSourceMGI: 1096327PubMedEurope PMCNat Metab 4:1369-1401 (2022)Mapped to40
Loss of Wiz Function Affects Methylation Pattern in Palate Development and Leads to Cleft Palate.Bukova I., Szczerkowska K.I., Prochazkova M., Beck I.M., Prochazka J., Sedlacek R.View abstractCategoriesFunctionSourceMGI: 1096327PubMedEurope PMCFront Cell Dev Biol 9:620692-620692 (2021)Mapped to91