Q7T3Q3 · Q7T3Q3_DANRE

Function

function

G-protein coupled receptor for cannabinoids. Mediates many cannabinoid-induced effects in the central nervous system (CNS), as well as in peripheral tissues. Signaling typically involves reduction in cyclic AMP.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentaxon
Cellular Componentcytoplasm
Cellular Componentmitochondrial outer membrane
Cellular Componentplasma membrane
Cellular Componentpresynapse
Molecular Functioncannabinoid receptor activity
Molecular FunctionG protein-coupled receptor activity
Biological Processadenylate cyclase-activating G protein-coupled receptor signaling pathway
Biological Processaxonal fasciculation
Biological Processaxonogenesis
Biological Processlipid biosynthetic process
Biological Processliver development
Biological Processmethionine metabolic process
Biological Processpositive regulation of feeding behavior
Biological Processregulation of metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Cannabinoid receptor

Gene names

    • Name
      cnr1
    • Synonyms
      cb1
      , CB1R

Organism names

  • Taxonomic identifier
  • Strain
    • Tuebingen
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    Q7T3Q3
  • Secondary accessions
    • A0A8N7V0B9

Proteomes

Organism-specific databases

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Mitochondrion outer membrane
Presynapse

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane125-149Helical
Transmembrane161-183Helical
Transmembrane195-220Helical
Transmembrane241-263Helical
Transmembrane283-307Helical
Transmembrane353-373Helical
Transmembrane385-407Helical

Keywords

PTM/Processing

Keywords

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain141-405G-protein coupled receptors family 1 profile

Sequence similarities

Belongs to the G-protein coupled receptor 1 family.

Keywords

Phylogenomic databases

Family and domain databases

Protein family/group databases

Sequence

  • Sequence status
    Complete
  • Length
    475
  • Mass (Da)
    53,044
  • Last updated
    2003-10-01 v1
  • Checksum
    98FEF62D883605D4
MLFPASKSDVKSVLDGVAETTFRTITSGLQYIGSNDIGYDDHIIDGDFSKSGYPLPKPFAAYRRSSFADKVAPDEELIVKGLPFYPTNSSDVFGNWSHAEDGSLQCGENFMDMECFMILTPSQQLAIAVLSLTLGTFTVLENLVVLCVILQSRTLRCRPSYHFIGSLAIADLLGSVIFVYSFLDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYVSIHRPLSYRRIVTRTKAVIAFCMMWAISIIIAVLPLLGWNCKRLNSVCSDIFPLIDENYLMFWIGVTSVLVLFIIYAYMYILWKAHHHAVRMLRRTSQKSLVVHSADGTKVQTPRPDQARMDIRLAKTLVLILVVLVICWGPLLAIMVYDLFWRMGDNIKTVFAFCSMLTLLNSTVNPIIYALRSKDLRRAFLAACQGCRGTSTTPLQLDNSLESDCHRNQHRAAESCVKTTVKIAKLTMSVSAETSAEAV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX537259
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AY148349
EMBL· GenBank· DDBJ
AAN46748.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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