Q7T0B0 · STK40_XENTR

Function

function

May be a negative regulator of NF-kappa-B and p53-mediated gene transcription.

Caution

Was originally thought to originate from X.laevis. However, sequence identity with X.tropicalis is much higher than with X.laevis, suggesting that the sequence is from X.tropicalis.

Catalytic activity

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site41-49ATP (UniProtKB | ChEBI)
Binding site66ATP (UniProtKB | ChEBI)
Active site197Proton acceptor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular FunctionATP binding
Molecular Functionprotein serine kinase activity
Molecular Functionprotein serine/threonine kinase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Serine/threonine-protein kinase 40
  • EC number
  • Alternative names
    • Serine/threonine-protein kinase lyk4

Gene names

    • Name
      stk40

Organism names

Accessions

  • Primary accession
    Q7T0B0
  • Secondary accessions
    • B1H340

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002522661-443Serine/threonine-protein kinase 40

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-26Disordered
Domain35-332Protein kinase

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    443
  • Mass (Da)
    50,140
  • Last updated
    2019-02-13 v2
  • Checksum
    606C8D1B179D133E
MKRRASERDAGETSARSKALCSSISGSNAKRAGPFILGPRLGNSPVPSIVQCLARKDGTDDFYQLKILSLEERGDKAGETQEERQGKMLLHTEYSLLSLLHNQDGVVHHHGLFQDRTCEIVEDLEANKLVRKMRKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLGERETVVIFYDVVRVVEALHKKNIVHRDLKLGNMVLNKRTHRITVTNFCLGKHLVSEDDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYSIPEDGRVSESTVCLIRKLLVLDPQQRLTASEVLESLGAIISSWQSMSSLSGPLQVVPDIDHLTSLENSQEAKVTEESSQYEFENYMRQQLLLAEEKNTIHEAKNFPQKRHFGNFPPIRRLGYDAQPVSPLDAAILAQRYLPPPHMALSNSH

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict16in Ref. 1; AAQ01592
Sequence conflict71in Ref. 1; AAQ01592
Sequence conflict73in Ref. 1; AAQ01592

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY336058
EMBL· GenBank· DDBJ
AAQ01592.1
EMBL· GenBank· DDBJ
mRNA
AAMC01091013
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AAMC01091014
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
BC161237
EMBL· GenBank· DDBJ
AAI61237.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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