Q7SZM0 · Q7SZM0_DANRE

Function

function

Receptor for ATP that acts as a ligand-gated ion channel.

Features

Showing features for binding site.

139850100150200250300350
TypeIDPosition(s)Description
Binding site71-73ATP (UniProtKB | ChEBI)
Binding site186ATP (UniProtKB | ChEBI)
Binding site296-298ATP (UniProtKB | ChEBI)
Binding site315ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Cellular Componentpostsynapse
Molecular FunctionATP binding
Molecular Functionextracellularly ATP-gated monoatomic cation channel activity
Molecular Functionpurinergic nucleotide receptor activity
Biological Processcalcium ion transmembrane transport
Biological Processresponse to ATP

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    P2X purinoceptor

Gene names

    • Name
      p2rx1
    • Synonyms
      p2xr1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    Q7SZM0

Proteomes

    • Identifier
    • Component
      Alternate scaffold 5, Chromosome 5

Organism-specific databases

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane32-53Helical
Transmembrane341-363Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for disulfide bond, glycosylation.

TypeIDPosition(s)Description
Disulfide bond119↔165
Disulfide bond129↔152
Disulfide bond135↔159
Glycosylation184N-linked (GlcNAc...) asparagine
Disulfide bond217↔227
Disulfide bond261↔270

Keywords

Interaction

Subunit

Functional P2XRs are organized as homomeric and heteromeric trimers.

Family & Domains

Sequence similarities

Belongs to the P2X receptor family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    398
  • Mass (Da)
    45,129
  • Last updated
    2003-10-01 v1
  • Checksum
    5960EC16693B00A3
MTRMKSAIKKTFSNFFFEYETPREVLVKNRRVAIVCRIIQLGVLAYIIGWVFMYEKGYQTVDNAIGSVFTKMKGVSFTNISGQERIWDVADYVFPEQGDSSFVVMTNFIPTIGQVQGKCPELPDGKNKCTNDSDCDDSKYKRTGNGHMTGRCMNKTQTCEIYSWCPVEDDRKIPDPPILLTAENYTLFIKNSITFPQFDVVRSNLVEGIDQNYINNCVYHPKTAPLCPIFRLGDIVERYGFSFSEIARVGGAIGVLIDWDCNLDLSIRFCKPKYEFYGLYGTGKNDQVDKASLGYNFRFAKYYVENSVQKRTLMKVFGVRIDIIVHGLAGKFDIIPTLTAIGSGVGIFGVATVVCDLLLLYILPKKNFYKTMKFKDAEICEETPALPQTQEDSESQKE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY292649
EMBL· GenBank· DDBJ
AAQ21194.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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