Q7SXH8 · Q7SXH8_DANRE
- ProteinProthrombin
- Genef2
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids524 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
Catalytic activity
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 305 | Charge relay system | ||||
Sequence: H | ||||||
Active site | 361 | Charge relay system | ||||
Sequence: D | ||||||
Active site | 466 | Charge relay system | ||||
Sequence: S |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | collagen-containing extracellular matrix | |
Cellular Component | extracellular space | |
Molecular Function | calcium ion binding | |
Molecular Function | serine-type endopeptidase activity | |
Molecular Function | serine-type peptidase activity | |
Biological Process | acute-phase response | |
Biological Process | blood coagulation | |
Biological Process | platelet activation | |
Biological Process | positive regulation of blood coagulation | |
Biological Process | proteolysis |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameProthrombin
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionQ7SXH8
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-23 | |||||
Sequence: MGAKLAPLLLFLLFGQVFHLTLC | ||||||
Chain | PRO_5035035930 | 24-524 | Prothrombin | |||
Sequence: HNVFINNKEASQIIRAKRANTVFEELKPGNLERECVEEICDHEEAREVFERVDKTEIFWAKYLGCEGTTLSRTPQNINSLRICATTEGDCFINIGAKYAGKVSVTKSGKACQYWKSNFPHKIDEFNVTQLKLQENFCRNPDKHKDGPWCFTRDPTVRRETCNVPKCGEAVVPPPKAPLDKFVEEGGGRERTTLDQRKAFFNPRSFGNGELDCGERPLFEKINKADKNEKELLMSYTGSRIVGGDEAEVASAPWQVMLYKRSPQELLCGASLISDEWILTAAHCILYPPWNKNFTINDIIVRLGKHSRTKYERGIEKIVAIDEIIVHPKYNWKENLNRDIALLHMKKPVVFTSEIHPVCLPTKSIAKNLMFAGYKGRVTGWGNLRESWTSNPSNLPAVLQQIHLPIVDQSICRNSTSVIITDNMFCAGYQPDDSKRGDACEGDSGGPFVMKSPSDNRWYQIGIVSWGEGCDRDGKYGFYTHLFRMRRWMKKVIEKTDSGDDE |
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 41-87 | Gla | ||||
Sequence: RANTVFEELKPGNLERECVEEICDHEEAREVFERVDKTEIFWAKYLG | ||||||
Domain | 112-189 | Kringle | ||||
Sequence: DCFINIGAKYAGKVSVTKSGKACQYWKSNFPHKIDEFNVTQLKLQENFCRNPDKHKDGPWCFTRDPTVRRETCNVPKC | ||||||
Domain | 263-516 | Peptidase S1 | ||||
Sequence: IVGGDEAEVASAPWQVMLYKRSPQELLCGASLISDEWILTAAHCILYPPWNKNFTINDIIVRLGKHSRTKYERGIEKIVAIDEIIVHPKYNWKENLNRDIALLHMKKPVVFTSEIHPVCLPTKSIAKNLMFAGYKGRVTGWGNLRESWTSNPSNLPAVLQQIHLPIVDQSICRNSTSVIITDNMFCAGYQPDDSKRGDACEGDSGGPFVMKSPSDNRWYQIGIVSWGEGCDRDGKYGFYTHLFRMRRWMKKVIE |
Sequence similarities
Belongs to the osteocalcin/matrix Gla protein family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length524
- Mass (Da)59,560
- Last updated2003-10-01 v1
- Checksum1B4AE08119080325
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
E7FAN5 | E7FAN5_DANRE | f2 | 635 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BC055596 EMBL· GenBank· DDBJ | AAH55596.1 EMBL· GenBank· DDBJ | mRNA |