Q7S6F3 · DBP9_NEUCR
- ProteinATP-dependent RNA helicase dbp-9
- Genedbp-9
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids676 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
Catalytic activity
- ATP + H2O = ADP + phosphate + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 139-146 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | nucleolus | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | DNA helicase activity | |
Molecular Function | DNA/RNA helicase activity | |
Molecular Function | RNA binding | |
Molecular Function | RNA helicase activity | |
Biological Process | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameATP-dependent RNA helicase dbp-9
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Sordariomycetidae > Sordariales > Sordariaceae > Neurospora
Accessions
- Primary accessionQ7S6F3
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000232344 | 1-676 | ATP-dependent RNA helicase dbp-9 | ||
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, motif, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-97 | Disordered | |||
Compositional bias | 23-47 | Basic and acidic residues | |||
Compositional bias | 48-65 | Polar residues | |||
Compositional bias | 66-97 | Basic and acidic residues | |||
Motif | 95-123 | Q motif | |||
Domain | 126-304 | Helicase ATP-binding | |||
Motif | 251-254 | DEAD box | |||
Domain | 317-541 | Helicase C-terminal | |||
Region | 410-444 | Disordered | |||
Region | 633-676 | Disordered | |||
Compositional bias | 646-676 | Basic residues | |||
Domain
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence similarities
Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length676
- Mass (Da)76,617
- Last updated2003-12-15 v1
- MD5 ChecksumE90C62C8D9A2D657296B9875B9285780
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 23-47 | Basic and acidic residues | |||
Compositional bias | 48-65 | Polar residues | |||
Compositional bias | 66-97 | Basic and acidic residues | |||
Compositional bias | 646-676 | Basic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CM002241 EMBL· GenBank· DDBJ | EAA31099.1 EMBL· GenBank· DDBJ | Genomic DNA |