Q7RTM4 · Q7RTM4_HUMAN
- ProteinSpectrin-like protein of the nuclear envelope and Golgi
- GeneSYNE1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids8407 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | cytoskeleton | |
Cellular Component | nuclear outer membrane | |
Molecular Function | actin binding |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionQ7RTM4
Subcellular Location
UniProt Annotation
GO Annotation
Nucleus outer membrane ; Single-pass type IV membrane protein
Features
Showing features for topological domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Topological domain | 1-8356 | Cytoplasmic | |||
Topological domain | 8378-8407 | Perinuclear space | |||
Keywords
- Cellular component
PTM/Processing
Proteomic databases
Structure
Family & Domains
Features
Showing features for domain, coiled coil, region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 27-134 | Calponin-homology (CH) | |||
Domain | 178-283 | Calponin-homology (CH) | |||
Coiled coil | 629-656 | ||||
Coiled coil | 1381-1408 | ||||
Coiled coil | 1696-1730 | ||||
Coiled coil | 2017-2071 | ||||
Coiled coil | 2274-2301 | ||||
Coiled coil | 2379-2413 | ||||
Coiled coil | 3971-4029 | ||||
Coiled coil | 4518-4552 | ||||
Coiled coil | 4813-4870 | ||||
Coiled coil | 5028-5055 | ||||
Coiled coil | 5081-5111 | ||||
Coiled coil | 5179-5264 | ||||
Coiled coil | 5343-5418 | ||||
Region | 5469-5496 | Disordered | |||
Compositional bias | 5472-5496 | Polar residues | |||
Coiled coil | 5668-5695 | ||||
Coiled coil | 5772-5799 | ||||
Coiled coil | 5837-5864 | ||||
Coiled coil | 6667-6694 | ||||
Coiled coil | 6773-6803 | ||||
Coiled coil | 7422-7449 | ||||
Region | 7856-7889 | Disordered | |||
Compositional bias | 7857-7877 | Polar residues | |||
Compositional bias | 8281-8341 | Polar residues | |||
Region | 8281-8344 | Disordered | |||
Domain | 8348-8407 | KASH | |||
Sequence similarities
Belongs to the nesprin family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length8,407
- Mass (Da)966,341
- Last updated2003-12-15 v1
- ChecksumF279F81908452D3D
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 5472-5496 | Polar residues | |||
Compositional bias | 7857-7877 | Polar residues | |||
Compositional bias | 8281-8341 | Polar residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BK000543 EMBL· GenBank· DDBJ | DAA01060.1 EMBL· GenBank· DDBJ | mRNA |