Q7RTM4 · Q7RTM4_HUMAN

  • Protein
    Spectrin-like protein of the nuclear envelope and Golgi
  • Gene
    SYNE1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    2/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentcytoskeleton
Cellular Componentnuclear outer membrane
Molecular Functionactin binding

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Spectrin-like protein of the nuclear envelope and Golgi

Gene names

    • Name
      SYNE1

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    Q7RTM4

Subcellular Location

Cytoplasm, cytoskeleton
Nucleus outer membrane
; Single-pass type IV membrane protein

Features

Showing features for topological domain.

TypeIDPosition(s)Description
Topological domain1-8356Cytoplasmic
Topological domain8378-8407Perinuclear space

Keywords

PTM/Processing

Proteomic databases

Family & Domains

Features

Showing features for domain, coiled coil, region, compositional bias.

Type
IDPosition(s)Description
Domain27-134Calponin-homology (CH)
Domain178-283Calponin-homology (CH)
Coiled coil629-656
Coiled coil1381-1408
Coiled coil1696-1730
Coiled coil2017-2071
Coiled coil2274-2301
Coiled coil2379-2413
Coiled coil3971-4029
Coiled coil4518-4552
Coiled coil4813-4870
Coiled coil5028-5055
Coiled coil5081-5111
Coiled coil5179-5264
Coiled coil5343-5418
Region5469-5496Disordered
Compositional bias5472-5496Polar residues
Coiled coil5668-5695
Coiled coil5772-5799
Coiled coil5837-5864
Coiled coil6667-6694
Coiled coil6773-6803
Coiled coil7422-7449
Region7856-7889Disordered
Compositional bias7857-7877Polar residues
Compositional bias8281-8341Polar residues
Region8281-8344Disordered
Domain8348-8407KASH

Sequence similarities

Belongs to the nesprin family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    8,407
  • Mass (Da)
    966,341
  • Last updated
    2003-12-15 v1
  • Checksum
    F279F81908452D3D

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias5472-5496Polar residues
Compositional bias7857-7877Polar residues
Compositional bias8281-8341Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BK000543
EMBL· GenBank· DDBJ
DAA01060.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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