Q7PYF4 · GR24_ANOGA
- ProteinGustatory and odorant receptor 24
- GeneGPRgr24
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids457 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
function
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. GPRgr22 and GPRgr24 together are sufficient for olfactory carbon dioxide-chemosensation.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspect | Term | |
---|---|---|
Cellular Component | axon | |
Cellular Component | dendrite | |
Cellular Component | membrane | |
Cellular Component | neuronal cell body | |
Cellular Component | plasma membrane | |
Molecular Function | olfactory receptor activity | |
Molecular Function | sweet taste receptor activity | |
Molecular Function | taste receptor activity | |
Biological Process | response to carbon dioxide | |
Biological Process | sensory perception of smell | |
Biological Process | sensory perception of taste | |
Biological Process | signal transduction |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameGustatory and odorant receptor 24
Gene names
Organism names
- Strains
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Nematocera > Culicoidea > Culicidae > Anophelinae > Anopheles
Accessions
- Primary accessionQ7PYF4
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 1-115 | Cytoplasmic | ||||
Sequence: MSLYFNADTMRIERSSVHEPKRNRNVFLDVKPIADDANVNVPPRQAARRNATVFNNRVGFPPLTPKEAFVDAVPADQTCMVFESSKPIYLVLRAIGVLPYTRLPSGGTAFVLASP | ||||||
Transmembrane | 116-136 | Helical; Name=1 | ||||
Sequence: SMTYCVLFFLLLTVYIAFILL | ||||||
Topological domain | 137-152 | Extracellular | ||||
Sequence: NRIEIVRTLEGRFEES | ||||||
Transmembrane | 153-173 | Helical; Name=2 | ||||
Sequence: VIAYLFIVNILPILIIPLMWY | ||||||
Topological domain | 174-209 | Cytoplasmic | ||||
Sequence: ESRKVVSVVNGWVDFETVYRETTGRALELRLRTKAQ | ||||||
Transmembrane | 210-230 | Helical; Name=3 | ||||
Sequence: VIAILLPILCSLSVAITHVTM | ||||||
Topological domain | 231-237 | Extracellular | ||||
Sequence: VDFKLLQ | ||||||
Transmembrane | 238-258 | Helical; Name=4 | ||||
Sequence: VIPYCVLDTITYMMGGYWYMA | ||||||
Topological domain | 259-309 | Cytoplasmic | ||||
Sequence: CETLSITAKILAEDFQRALRHVGPAAKVSEYRSLWLRLSKLARDTGFSTCY | ||||||
Transmembrane | 310-330 | Helical; Name=5 | ||||
Sequence: TFTFICLYLFFIITLSIYGLM | ||||||
Topological domain | 331-341 | Extracellular | ||||
Sequence: SQISDGFGVKD | ||||||
Transmembrane | 342-362 | Helical; Name=6 | ||||
Sequence: IGLAVTAFCSVGLLFYICDEA | ||||||
Topological domain | 363-421 | Cytoplasmic | ||||
Sequence: HYASFNVRTNFQKKLLMVELSWMNTDAQTEINMFLRATEMNPSSINLGGFFDVNRTLFK | ||||||
Transmembrane | 422-442 | Helical; Name=7 | ||||
Sequence: SLLATMVTYLVVLLQFQISIP | ||||||
Topological domain | 443-457 | Extracellular | ||||
Sequence: DEPSAMLMHSNSSHS |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain, glycosylation.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000296318 | 1-457 | Gustatory and odorant receptor 24 | |||
Sequence: MSLYFNADTMRIERSSVHEPKRNRNVFLDVKPIADDANVNVPPRQAARRNATVFNNRVGFPPLTPKEAFVDAVPADQTCMVFESSKPIYLVLRAIGVLPYTRLPSGGTAFVLASPSMTYCVLFFLLLTVYIAFILLNRIEIVRTLEGRFEESVIAYLFIVNILPILIIPLMWYESRKVVSVVNGWVDFETVYRETTGRALELRLRTKAQVIAILLPILCSLSVAITHVTMVDFKLLQVIPYCVLDTITYMMGGYWYMACETLSITAKILAEDFQRALRHVGPAAKVSEYRSLWLRLSKLARDTGFSTCYTFTFICLYLFFIITLSIYGLMSQISDGFGVKDIGLAVTAFCSVGLLFYICDEAHYASFNVRTNFQKKLLMVELSWMNTDAQTEINMFLRATEMNPSSINLGGFFDVNRTLFKSLLATMVTYLVVLLQFQISIPDEPSAMLMHSNSSHS | ||||||
Glycosylation | 453 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N |
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Tissue specificity
Carbon dioxide-responsive neurons coexpress GPRgr22 and GPRgr24 in the maxillary palp, at both larval and adult life stages.
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Sequence similarities
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length457
- Mass (Da)51,736
- Last updated2012-04-18 v4
- ChecksumDE4A271B147F1847
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 196 | in Ref. 2; ABK97614 | ||||
Sequence: T → S |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AAAB01008987 EMBL· GenBank· DDBJ | EAA01019.4 EMBL· GenBank· DDBJ | Genomic DNA | ||
DQ989013 EMBL· GenBank· DDBJ | ABK97614.1 EMBL· GenBank· DDBJ | mRNA |