Q7NWJ5 · ASSY_CHRVO
- ProteinArgininosuccinate synthase
- GeneargG
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids408 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- L-citrulline + L-aspartate + ATP = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H+
Pathway
Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 10-18 | ATP (UniProtKB | ChEBI) | |||
Binding site | 37 | ATP (UniProtKB | ChEBI) | |||
Binding site | 90 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 95 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 120 | ATP (UniProtKB | ChEBI) | |||
Binding site | 122 | L-aspartate (UniProtKB | ChEBI) | |||
Binding site | 126 | L-aspartate (UniProtKB | ChEBI) | |||
Binding site | 126 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 127 | L-aspartate (UniProtKB | ChEBI) | |||
Binding site | 130 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 181 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 190 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 266 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 278 | L-citrulline (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | argininosuccinate synthase activity | |
Molecular Function | ATP binding | |
Biological Process | arginine biosynthetic process | |
Biological Process | argininosuccinate metabolic process | |
Biological Process | urea cycle |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameArgininosuccinate synthase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Neisseriales > Chromobacteriaceae > Chromobacterium
Accessions
- Primary accessionQ7NWJ5
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000148584 | 1-408 | Argininosuccinate synthase | ||
Interaction
Structure
Sequence
- Sequence statusComplete
- Length408
- Mass (Da)45,668
- Last updated2003-12-15 v1
- Checksum99C9F4CE0FF3C1FC
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE016825 EMBL· GenBank· DDBJ | AAQ59666.1 EMBL· GenBank· DDBJ | Genomic DNA |