Q7N288 · FADJ_PHOLL

Function

function

Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.

Catalytic activity

Pathway

Lipid metabolism; fatty acid beta-oxidation.

Features

Showing features for site.

TypeIDPosition(s)Description
Site133Important for catalytic activity
Site155Important for catalytic activity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function3-hydroxyacyl-CoA dehydrogenase activity
Molecular Function3-hydroxybutyryl-CoA epimerase activity
Molecular Functionenoyl-CoA hydratase activity
Molecular FunctionNAD+ binding
Biological Processfatty acid beta-oxidation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Fatty acid oxidation complex subunit alpha

Including 2 domains:

  • Recommended name
    Enoyl-CoA hydratase/3-hydroxybutyryl-CoA epimerase
  • EC number
  • Recommended name
    3-hydroxyacyl-CoA dehydrogenase
  • EC number

Gene names

    • Name
      fadJ
    • Ordered locus names
      plu3200

Organism names

Accessions

  • Primary accession
    Q7N288

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001093031-727Fatty acid oxidation complex subunit alpha

Interaction

Subunit

Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region16-205Enoyl-CoA hydratase
Region321-7273-hydroxyacyl-CoA dehydrogenase

Sequence similarities

In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    727
  • Mass (Da)
    79,265
  • Last updated
    2005-12-06 v2
  • Checksum
    5173D0EE51FB2930
MTQAQHDAAPITTGTNQTASVFSFDVRPDKIGIITINVPGEKVNTLKAEFVDQFLNVFKQAQQSSGLKGLILISGKPDTFIAGADISMIAGCKTKEDARDLAEKGQKLFSQIANYPLPVVAAIHGACLGGGLELALACHWRVCSQDDKTRLGLPEVQLGLLPGSGGTQRLPRLIGVSSALDIMLTGKQLRAKQALRLGLVDDAVPLDILLDIAIEKVKKGIPVRKPLPWQQRLLVGPVGRYFLFNIVRKKTLAKTRGHYPAPERIIEVVKEGLEKGMSQGLRAEAVAFGELAMTRESAALRNLFFAATSLKNETGSSEKPAKIKHVGILGGGLMGGGIANVTATRGKLPVRIKDINEKGISQVLKYTWDLLSKRVKQKRLRPAERAQQMMLISGTTDYRGFAQTDIVVEAVFEDLSLKQKMVAEIETNAKPETIFASNTSSLPIHQIAEKAQRPEQVIGLHYFSPVDKMPLVEVIPHQGTSEKTIATAVSLAKKQGKTAIVVGDKAGFYVNRILVPYISEAAHCLVAGEPIDHIDGALVNFGFPVGPINLLDEVGIDVGTKIMPVLVEQLGPRFAAPESLDAVLKDGRKGRKNGRGFYLYAPGPRKFWQFGKRDKKVDSSVYTLLNITPESHMLSSEIAQRCVMLMLNEAVRCLDEGIIRSPRDGDIGAVFGIGFPPFFGGPFRYIDSLGCARVVEILRRLESQYGDRFVPCECLVNMAEQNKSFYP

Sequence caution

The sequence CAE15574.1 differs from that shown. Reason: Erroneous initiation

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX571869
EMBL· GenBank· DDBJ
CAE15574.1
EMBL· GenBank· DDBJ
Genomic DNA Different initiation

Genome annotation databases

Similar Proteins

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