Q7N0A6 · IDI2_PHOLL

Function

function

Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit. The magnesium ion binds only when substrate is bound.
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Binds 1 Mn2+ ion per subunit.

Pathway

Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from isopentenyl diphosphate: step 1/1.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site24Mn2+ (UniProtKB | ChEBI)
Binding site30Mn2+ (UniProtKB | ChEBI)
Active site65
Binding site65Mg2+ (UniProtKB | ChEBI)
Binding site67Mn2+ (UniProtKB | ChEBI)
Binding site85Mg2+ (UniProtKB | ChEBI)
Binding site110Mn2+ (UniProtKB | ChEBI)
Active site112
Binding site112Mn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionisopentenyl-diphosphate delta-isomerase activity
Molecular Functionmetal ion binding
Biological Processdimethylallyl diphosphate biosynthetic process
Biological Processisoprenoid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Isopentenyl-diphosphate Delta-isomerase 2
  • EC number
  • Short names
    IPP isomerase 2
  • Alternative names
    • IPP:DMAPP isomerase 2
    • Isopentenyl pyrophosphate isomerase 2

Gene names

    • Name
      idi2
    • Ordered locus names
      plu3987

Organism names

Accessions

  • Primary accession
    Q7N0A6

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002052581-177Isopentenyl-diphosphate Delta-isomerase 2

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain28-160Nudix hydrolase

Sequence similarities

Belongs to the IPP isomerase type 1 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    177
  • Mass (Da)
    20,340
  • Last updated
    2003-12-15 v1
  • Checksum
    43BE9A99A0EEE46A
MDEILVLVDKHDNPIGSAGKADIHQKGMLHRAFSIFVFDNKGNLLLQKRAATKYHSAGLWTNSCCGHPRVGEALEAAAHRRLGEEMGFDCPLKKVSSFIYHAILPNNLIEYEYDHVFIGRFDKEPIINLDEVSDYKWVNLLKLRALINNAPDVYTVWFKKIINGLSYQDIEEWQRLI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX571872
EMBL· GenBank· DDBJ
CAE16359.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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