Q7MZ18 · OTC_PHOLL
- ProteinOrnithine carbamoyltransferase
- GeneargI
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids338 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
Catalytic activity
- carbamoyl phosphate + L-ornithine = L-citrulline + phosphate + H+
Pathway
Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 1/3.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 56-59 | carbamoyl phosphate (UniProtKB | ChEBI) | |||
Binding site | 83 | carbamoyl phosphate (UniProtKB | ChEBI) | |||
Binding site | 107 | carbamoyl phosphate (UniProtKB | ChEBI) | |||
Binding site | 134-137 | carbamoyl phosphate (UniProtKB | ChEBI) | |||
Binding site | 168 | L-ornithine (UniProtKB | ChEBI) | |||
Binding site | 232 | L-ornithine (UniProtKB | ChEBI) | |||
Binding site | 236-237 | L-ornithine (UniProtKB | ChEBI) | |||
Binding site | 274-275 | carbamoyl phosphate (UniProtKB | ChEBI) | |||
Binding site | 320 | carbamoyl phosphate (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | amino acid binding | |
Molecular Function | ornithine carbamoyltransferase activity | |
Biological Process | arginine biosynthetic process via ornithine | |
Biological Process | citrulline biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameOrnithine carbamoyltransferase
- EC number
- Short namesOTCase
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Morganellaceae > Photorhabdus
Accessions
- Primary accessionQ7MZ18
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000112978 | 1-338 | Ornithine carbamoyltransferase | ||
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length338
- Mass (Da)37,805
- Last updated2003-12-15 v1
- MD5 Checksum5478A178E71311260F7F70A574C37E01
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BX571874 EMBL· GenBank· DDBJ | CAE16862.1 EMBL· GenBank· DDBJ | Genomic DNA |