Q7M756 · PRS54_MOUSE

  • Protein
    Inactive serine protease 54
  • Gene
    Prss54
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

Caution

Although related to peptidase S1 family, lacks the essential His, Asp, and Ser residues of the catalytic triad at positions 73, 119 and 210 and is therefore predicted to have lost protease activity.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular region
Molecular Functionserine-type endopeptidase activity
Biological Processproteolysis

Keywords

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Inactive serine protease 54
  • Alternative names
    • Plasma kallikrein-like protein 4

Gene names

    • Name
      Prss54
    • Synonyms
      Klkbl4

Organism names

  • Taxonomic identifier
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q7M756

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain, glycosylation, disulfide bond.

Type
IDPosition(s)Description
Signal1-20
ChainPRO_500009597321-383Inactive serine protease 54
Glycosylation113N-linked (GlcNAc...) asparagine
Disulfide bond154↔216
Disulfide bond185↔195
Disulfide bond206↔237

Keywords

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Miscellaneous

Structure

Family & Domains

Features

Showing features for domain, region.

Type
IDPosition(s)Description
Domain21-258Peptidase S1
Region305-334Disordered

Sequence similarities

Belongs to the peptidase S1 family. Plasma kallikrein subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    383
  • Mass (Da)
    42,758
  • Last updated
    2003-12-15 v1
  • Checksum
    982B61714A56FC95
MAEMRGMLLMLLYISHSSSAICGIQKATIADKLKENLVSSTEFPWVVSIQDKQYTHLAFGCILSEFWILSTASALQHRPEVIAVVGISNMDPRKTDHREYSVNTIIPHENFDNVSMGNNIALLKTESAMHFNDLVQAICFLGKKLHKPPALKNCWVAGWNPTSATGNHMTMSILRRISVKDIEVCPLRRHQKTECASHTKEPNNVCLGEPGSPMMCQAKKLDLWILRGLLAYGGDSCPGLFLYTSVADYSDWITAKTRKAGPSLSSLHLWEKLVFELPFHESNIALTTNSFSIHTYAEWPHSYSQGQRMSTKSNKQKDAGQNFRVNRQPETSGPSKVAIQPMYYDYYGGEAGEGGAVAGQNRLHWSQERILMSFVLVFLGSGV

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A6H685A6H685_MOUSEPrss54383

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC102555
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
CAAA01187779
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
BN000132
EMBL· GenBank· DDBJ
CAD67595.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help