Q7M709 · TR129_MOUSE
- ProteinTaste receptor type 2 member 129
- GeneTas2r129
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids320 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Putative taste receptor which may play a role in the perception of bitterness.
Miscellaneous
Several bitter taste receptors are expressed in a single taste receptor cell.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | bitter taste receptor activity | |
Molecular Function | G protein-coupled receptor activity | |
Biological Process | detection of chemical stimulus involved in sensory perception of bitter taste |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameTaste receptor type 2 member 129
- Short namesT2R129; mT2R60
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionQ7M709
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 1-8 | Extracellular | ||||
Sequence: MDGIVQNM | ||||||
Transmembrane | 9-29 | Helical; Name=1 | ||||
Sequence: FTFIVIVEIIIGWIGNGFIAL | ||||||
Topological domain | 30-55 | Cytoplasmic | ||||
Sequence: VNCIHWYKRRKISALNQILTALAFSR | ||||||
Transmembrane | 56-76 | Helical; Name=2 | ||||
Sequence: IYLLLTVFTVIAVSTLYTHVL | ||||||
Topological domain | 77-88 | Extracellular | ||||
Sequence: VTRRVVKLINFH | ||||||
Transmembrane | 89-109 | Helical; Name=3 | ||||
Sequence: LLFSNHFSMWLAACLGLYYFL | ||||||
Topological domain | 110-128 | Cytoplasmic | ||||
Sequence: KIAHFPNSIFVYLKMRINQ | ||||||
Transmembrane | 129-149 | Helical; Name=4 | ||||
Sequence: VVSGTLLMSLGLLFLNTLLIN | ||||||
Topological domain | 150-185 | Extracellular | ||||
Sequence: SYIDTKIDDYREHLLYDFTSNNTASFYRVILVINNC | ||||||
Transmembrane | 186-206 | Helical; Name=5 | ||||
Sequence: IFTSIPFTLSQSTFLLLIFSL | ||||||
Topological domain | 207-233 | Cytoplasmic | ||||
Sequence: WRHYKKMQQHAQRCRDVLADAHIRVLQ | ||||||
Transmembrane | 234-254 | Helical; Name=6 | ||||
Sequence: TMVTYVLLCAIFFLSLSMQIL | ||||||
Topological domain | 255-264 | Extracellular | ||||
Sequence: RSELLKNILY | ||||||
Transmembrane | 265-285 | Helical; Name=7 | ||||
Sequence: VRFCEIVAAVFPSGHSCVLIC | ||||||
Topological domain | 286-320 | Cytoplasmic | ||||
Sequence: RDTNLRGTFLSVLSWLKQRFTSWIPNINCRSSCIF |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain, glycosylation.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000248485 | 1-320 | Taste receptor type 2 member 129 | |||
Sequence: MDGIVQNMFTFIVIVEIIIGWIGNGFIALVNCIHWYKRRKISALNQILTALAFSRIYLLLTVFTVIAVSTLYTHVLVTRRVVKLINFHLLFSNHFSMWLAACLGLYYFLKIAHFPNSIFVYLKMRINQVVSGTLLMSLGLLFLNTLLINSYIDTKIDDYREHLLYDFTSNNTASFYRVILVINNCIFTSIPFTLSQSTFLLLIFSLWRHYKKMQQHAQRCRDVLADAHIRVLQTMVTYVLLCAIFFLSLSMQILRSELLKNILYVRFCEIVAAVFPSGHSCVLICRDTNLRGTFLSVLSWLKQRFTSWIPNINCRSSCIF | ||||||
Glycosylation | 170 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N |
Keywords
- PTM
Proteomic databases
PTM databases
Structure
Sequence
- Sequence statusComplete
- Length320
- Mass (Da)37,178
- Last updated2003-12-15 v1
- ChecksumF8DD1BCA7517300F
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC129318 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
BK001088 EMBL· GenBank· DDBJ | DAA01227.1 EMBL· GenBank· DDBJ | Genomic DNA |