Q7KK34 · Q7KK34_DROME
- ProteinRNA helicase
- GeneRs1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids641 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
Catalytic activity
- ATP + H2O = ADP + H+ + phosphate
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleolus | |
Molecular Function | ATP binding | |
Molecular Function | hydrolase activity | |
Molecular Function | nucleic acid binding | |
Molecular Function | RNA helicase activity | |
Biological Process | regulation of gene expression |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRNA helicase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionQ7KK34
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain, motif.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 87-147 | Disordered | ||||
Sequence: QKRGGAEAVAAEQSDGSEIDLSEDELKHDNLRLREKKESKKKKKKAGEEDEEDEGEKMQFA | ||||||
Compositional bias | 106-137 | Basic and acidic residues | ||||
Sequence: DLSEDELKHDNLRLREKKESKKKKKKAGEEDE | ||||||
Domain | 157-185 | DEAD-box RNA helicase Q | ||||
Sequence: TSFYQMNLSRPLMRAIGVLGYIYPTPIQA | ||||||
Motif | 157-185 | Q motif | ||||
Sequence: TSFYQMNLSRPLMRAIGVLGYIYPTPIQA | ||||||
Domain | 188-363 | Helicase ATP-binding | ||||
Sequence: IPVALLGRDICGCAATGTGKTAAYMLPTLERLLYRPLNNKAITRVLVLVPTRELGAQVYQVTKQLCQFTTIDVGLAIGGLDVKAQEAVLRQNPDIVIATPGRLIDHIKNTPSFTLDSIEVLILDEADRMLDEYFAEQMKEIINSCCKTRQTMLFSATMSEQVKDLAAVSLDKPIKV | ||||||
Domain | 374-554 | Helicase C-terminal | ||||
Sequence: NLRQEFIRIREDKEGDREPILASLICRTFHDHCMVFVQTKKQAHRLHILLGLLGVRAGELHGNLTQQQRLESLKKFKEEQIDVLIATDVAARGLDIVGVKTVINFVMPITTEHYIHRVGRTARAGRAGISVSLAGEKERKIVKDIIKNAESTIKNRIIPPEIIEKYRNKLTSLEPEIQNIL | ||||||
Compositional bias | 564-581 | Basic and acidic residues | ||||
Sequence: AKTEQQLSKTERKLLGQT | ||||||
Region | 564-641 | Disordered | ||||
Sequence: AKTEQQLSKTERKLLGQTNERRGWFQTKQQREAEKDRLALTTGDEDKASGGKGKGKTAGKRKRPEYGGDGEDGPPVKD | ||||||
Compositional bias | 588-616 | Basic and acidic residues | ||||
Sequence: FQTKQQREAEKDRLALTTGDEDKASGGKG | ||||||
Compositional bias | 623-641 | Basic and acidic residues | ||||
Sequence: KRKRPEYGGDGEDGPPVKD |
Sequence similarities
Belongs to the DEAD box helicase family. DDX27/DRS1 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusFragment
- Length641
- Mass (Da)72,148
- Last updated2004-07-05 v1
- ChecksumD5F0D0DB2B47B830
Features
Showing features for compositional bias, non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 106-137 | Basic and acidic residues | ||||
Sequence: DLSEDELKHDNLRLREKKESKKKKKKAGEEDE | ||||||
Compositional bias | 564-581 | Basic and acidic residues | ||||
Sequence: AKTEQQLSKTERKLLGQT | ||||||
Compositional bias | 588-616 | Basic and acidic residues | ||||
Sequence: FQTKQQREAEKDRLALTTGDEDKASGGKG | ||||||
Compositional bias | 623-641 | Basic and acidic residues | ||||
Sequence: KRKRPEYGGDGEDGPPVKD | ||||||
Non-terminal residue | 641 | |||||
Sequence: D |
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AF181659 EMBL· GenBank· DDBJ | AAD55444.1 EMBL· GenBank· DDBJ | mRNA |