BG5_Drosophila death-domain containing protein similar to cell death protein RIP.Zhou L., Steller H.Cited forNUCLEOTIDE SEQUENCE [MRNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)Submission Submitted to EMBL/GenBank/DDBJ databases (JAN-2000)Cited in1
The genome sequence of Drosophila melanogaster.Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A.[...], Venter J.C.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainBerkeleyCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCScience 287:2185-2195 (2000)Cited in99+99+Mapped to9
Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H.[...], Lewis S.E.View abstractCited forGENOME REANNOTATIONStrainBerkeleyCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenome Biol. 3:RESEARCH0083.1-RESEARCH0083.22 (2002)Cited in99+99+Mapped to25
A Drosophila full-length cDNA resource.Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A., Guarin H., Kronmiller B., Pacleb J.M.[...], Celniker S.E.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]StrainBerkeleyTissueHeadCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenome Biol. 3:RESEARCH0080.1-RESEARCH0080.8 (2002)Cited in99+Mapped to93
A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense.Lemaitre B., Kromer-Metzger E., Michaut L., Nicolas E., Meister M., Georgel P., Reichhart J.M., Hoffmann J.A.View abstractCited forFUNCTION, MUTAGENESIS OF ALA-31CategoriesFunction, Phenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 92:9465-9469 (1995)Cited in1Mapped to9
The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults.Lemaitre B., Nicolas E., Michaut L., Reichhart J.-M., Hoffmann J.A.View abstractCited forFUNCTION, MUTAGENESIS OF ALA-31CategoriesFunction, Phenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell 86:973-983 (1996)Cited in4Mapped to34
The Drosophila caspase Dredd is required to resist Gram-negative bacterial infection.Leulier F., Rodriguez A., Khush R.S., Abrams J.M., Lemaitre B.View abstractCited forFUNCTIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCEMBO Rep. 1:353-358 (2000)Cited in4Mapped to28
Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis.Georgel P., Naitza S., Kappler C., Ferrandon D., Zachary D., Swimmer C., Kopczynski C., Duyk G., Reichhart J.M., Hoffmann J.A.View abstractCited forFUNCTION, MUTAGENESIS OF ALA-31CategoriesFunction, Phenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCDev. Cell 1:503-514 (2001)Cited in1Mapped to24
The imd gene is required for local Cecropin expression in Drosophila barrier epithelia.Onfelt Tingvall T., Roos E., Engstroem Y.View abstractCited forFUNCTIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCEMBO Rep. 2:239-243 (2001)Cited in2
The Drosophila immune defense against Gram-negative infection requires the death protein dFADD.Naitza S., Rosse C., Kappler C., Georgel P., Belvin M., Gubb D., Camonis J., Hoffmann J.A., Reichhart J.-M.View abstractCited forFUNCTION, INTERACTION WITH FADDCategoriesFunction, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCImmunity 17:575-581 (2002)Cited in2Mapped to22
The Drosophila ubiquitin-specific protease dUSP36/Scny targets IMD to prevent constitutive immune signaling.Thevenon D., Engel E., Avet-Rochex A., Gottar M., Bergeret E., Tricoire H., Benaud C., Baudier J., Taillebourg E., Fauvarque M.O.View abstractCited forFUNCTION, INTERACTION WITH SCNY, DEUBIQUITINATION, DISRUPTION PHENOTYPECategoriesFunction, PTM / Processing, Interaction, Phenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell Host Microbe 6:309-320 (2009)Cited in2Mapped to23
A novel system for the launch of alphavirus RNA synthesis reveals a role for the Imd pathway in arthropod antiviral response.Avadhanula V., Weasner B.P., Hardy G.G., Kumar J.P., Hardy R.W.View abstractCited forFUNCTIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCPLoS Pathog. 5:E1000582-E1000582 (2009)Cited in1Mapped to36
Caspase-mediated cleavage, IAP binding, and ubiquitination: linking three mechanisms crucial for Drosophila NF-kappaB signaling.Paquette N., Broemer M., Aggarwal K., Chen L., Husson M., Ertuerk-Hasdemir D., Reichhart J.M., Meier P., Silverman N.View abstractCited forFUNCTION, INTERACTION WITH DIAP2, PHOSPHORYLATION, PROTEOLYTIC CLEAVAGE, UBIQUITINATION, MUTAGENESIS OF ASP-30CategoriesFunction, PTM / Processing, Interaction, Phenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell 37:172-182 (2010)Cited in1Mapped to27
fat facets induces polyubiquitination of Imd and inhibits the innate immune response in Drosophila.Yagi Y., Lim Y.M., Tsuda L., Nishida Y.View abstractCited forFUNCTION, INTERACTION WITH FAFCategoriesFunction, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenes Cells 18:934-945 (2013)Cited in2Mapped to22
Identifying USPs regulating immune signals in Drosophila: USP2 deubiquitinates Imd and promotes its degradation by interacting with the proteasome.Engel E., Viargues P., Mortier M., Taillebourg E., Coute Y., Thevenon D., Fauvarque M.O.View abstractCited forINTERACTION WITH USP2 AND RPT6, DEUBIQUITINATIONCategoriesPTM / Processing, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell Commun. Signal. 12:41-41 (2014)Cited in5Mapped to71
Analysis of the Drosophila host defense in domino mutant larvae, which are devoid of hemocytes.Braun A., Hoffmann J.A., Meister M.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0013983PubMedEurope PMCProc Natl Acad Sci U S A 95:14337-14342 (1998)Mapped to16
Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of-flight mass spectrometry study.Uttenweiler-Joseph S., Moniatte M., Lagueux M., van Dorsselaer A., Hoffmann J.A., Bulet P.View abstractCategoriesSequencesSourceFlyBase: FBgn0013983PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 95:11342-11347 (1998)Cited in13Mapped to14
Two distinct pathways can control expression of the gene encoding the Drosophila antimicrobial peptide metchnikowin.Levashina E.A., Ohresser S., Lemaitre B., Imler J.-L.View abstractCategoriesSequencesSourceFlyBase: FBgn0013983PubMedEurope PMCJ. Mol. Biol. 278:515-527 (1998)Cited in1Mapped to27
In vivo regulation of the IkappaB homologue cactus during the immune response of Drosophila.Nicolas E., Reichhart J.M., Hoffmann J.A., Lemaitre B.View abstractCategoriesFunctionSourceFlyBase: FBgn0013983PubMedEurope PMCJ Biol Chem 273:10463-10469 (1998)Mapped to22
Mammalian and Drosophila blood: JAK of all trades?Mathey-Prevot B., Perrimon N.CategoriesFunctionSourceFlyBase: FBgn0013983PubMedEurope PMCCell 92:697-700 (1998)Mapped to56
Regulated nuclear import of Rel proteins in the Drosophila immune response.Wu L.P., Anderson K.V.View abstractCategoriesFunctionSourceFlyBase: FBgn0013983PubMedEurope PMCNature 392:93-97 (1998)Mapped to33
Antimicrobial peptide defense in Drosophila.Meister M., Lemaitre B., Hoffmann J.A.View abstractCategoriesNamesSourceFlyBase: FBgn0013983PubMedEurope PMCBioessays 19:1019-1026 (1997)Mapped to35
Characterization of an immunodeficiency mutant in Drosophila.Corbo J.C., Levine M.View abstractCategoriesFunctionSourceFlyBase: FBgn0013983PubMedEurope PMCMech Dev 55:211-220 (1996)Mapped to6
IMD-mediated innate immune priming increases Drosophila survival and reduces pathogen transmission.Prakash A., Fenner F., Shit B., Salminen T.S., Monteith K.M., Khan I., Vale P.F.View abstractAnnotationIMD-mediated innate immune priming increases Drosophila survival and reduces pathogen transmission.SourceGeneRif: 44339PubMedEurope PMCPLoS Pathog 20:e1012308-e1012308 (2024)Mapped to1
Effects of tobacco smoke on the expression of virulence genes in <i>Escherichia coli</i>.Shiratsuchi A., Kidoura Y., Toriba A., Nakanishi Y., Nainu F.View abstractSourceFlyBase: FBgn0013983PubMedEurope PMCNarra J 4:e754-e754 (2024)Mapped to10