Q7K3H0 · Q7K3H0_DROME

Function

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentendosome membrane
Cellular Componentphosphatidylinositol 3-kinase complex
Cellular Componentplasma membrane
Molecular Function1-phosphatidylinositol-3-kinase activity
Molecular Function1-phosphatidylinositol-4-phosphate 3-kinase activity
Molecular Functionphosphatidylinositol binding
Molecular Functionphospholipid binding
Molecular FunctionSH3 domain binding
Molecular Functionsmall GTPase binding
Biological Processcortical actin cytoskeleton organization
Biological Processnegative regulation of epidermal growth factor receptor signaling pathway
Biological Processphosphatidylinositol 3-kinase/protein kinase B signal transduction
Biological Processphosphatidylinositol phosphate biosynthetic process
Biological Processphosphatidylinositol-3-phosphate biosynthetic process
Biological Processphosphatidylinositol-mediated signaling

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Submitted names
    • LD28067p
    • Phosphatidylinositol 3-kinase 68D, isoform A
      (EC:2.7.1.137
      , EC:2.7.1.154
      )
    • Phosphatidylinositol 3-kinase 68D, isoform C
    • Phosphatidylinositol 3-kinase 68D, isoform D

Gene names

    • Name
      Pi3K68D
    • Synonyms
      11621
      , BcDNA:LD15217
      , Cpk
      , cpk
      , Dmel\CG11621
      , dPI3K
      , dPI3k
      , dPIK
      , PI(3)K
      , PI3K
      , Pi3K
      , PI3K 68_D
      , PI3K 68D
      , PI3K-68D
      , PI3K-68D/E
      , PI3K68D
      , pi3k68d
      , PI3K_68D
      , PI[[3]]K
    • ORF names
      CG11621
      , Dmel_CG11621

Organism names

  • Taxonomic identifier
  • Strain
    • Berkeley
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    Q7K3H0

Proteomes

Organism-specific databases

PTM/Processing

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region31-95Disordered
Compositional bias39-63Polar residues
Compositional bias80-95Polar residues
Region260-336Disordered
Compositional bias268-299Polar residues
Compositional bias311-331Polar residues
Domain560-666PI3K-RBD
Domain849-1021C2 PI3K-type
Domain1029-1207PIK helical
Domain1296-1571PI3K/PI4K catalytic
Domain1609-1725PX
Domain1749-1868C2

Sequence similarities

Belongs to the PI3/PI4-kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,876
  • Mass (Da)
    210,475
  • Last updated
    2006-10-17 v1
  • Checksum
    BD1931D669A6B983
MSNQAHIDYDKQFQDDLAKATALSLEQHALDDYRRNKKYGSGYQQSSTVAGRDYQAAQRSQSLHQPRRHSEVHQVAISPENAERSRTPPAQGTDNDLICFASPTSKQPESSSPFGKLIEDLQRMQPTNPQSALVPMGPVASASIPPQYGFPPHQQRPTAAQPTPYGMVAGGVVGGPAYGDLQLVPYQPAAQQQRPLNSEELQRLYSMPAQMAVVPVPQPNAYMYYPGAVVTPYTAPIVPGSAAFMPPQYPAQGYGFGGAYTHMDLRRPQSQPAPQQTAPTTSHHHSQPSNHSTSSPAEANGVAFPARRQVPSTVGVSSSSHTGNNGHSSVPRRGNDLIDLNHEDYSRVSVLEAFDPLLNDNTGNDTASDSTSYYAEYDPFDFLYSGDAATQYSDPMYEAVNRWDKTVATVSPNVGLIGWRQDFLSQPSTSSSQYGVAPPEESLKLAENGSGTISPPPPLPPRNQQCYESNQAAMPVSRPPQSSVLTDSYTSSIPANVVLDRRKTCTRLYELISDQRTDDPELLEFYHMVKEVRARYPHDDAPTNVGHVVAAEFNYHYMMDTSIKVIVHPALNTLQSTVLAASMGKEQVKGYGMPVTFTCDIDSVVAQVVAQALASLEGQVKGTVTDYAVKPIGLLEWLAPTSRLSQLECVHNSFQLEKDVHLGLCLSTAANMQAIARTERDDEHDADLLPEHLLPNEVVPIVTYDNMMILIETLEMEIDKLESAADGVPGRSVVSCSGVVQAVKAICALLGSIDTMEIARCVADLKRICEVEQKKYSTGASNPEIVSDYGDYAQVVLRPRSMLEQIKVKCNELRDAVQELVELYANVFRVAFSVKTPDYSTTPIPISCVSKPIVVCISCLHRPLPNWKFDDYSLCVQIVYGTRLLSKPNVLTCSNDTSGGLFPRLNFSAWLTFDQHPICTLPREARLTFVLYGKQAASEGEPNADQNGERRQVTTELGWCSIQLFDFKRVMICGPYLLSLWPPMTDKMLGPAPARGCHPQPDFCPVLSIEVPPYGGRIEFPEHQEVPKPAPHYDFASLDANLQEELLDTAELGYTGATERREVFWEKRLYLQSYPNALPKVLHAAHSWDYANLIDLHALLHSWAPLSPLQSLELLLPRYPDAKVREKAVEWISKMPNDQLVDFLPQLVQSLKHDTYEGSAMARFLLSKCLESPRFAHHMYWLLVHSLPDDPHNSIGAAMVDQEYDESQVTQVRYYRRNKMMLRALMAICGEKMLQRFMYQHRMCQKLTTIAESVKEAKESMRQKSLAAGMDEVHQDLLEQPTCLPLGPELEVTGVSVRNCSYFNSNTLPLKINFVGPDAESLPAIFKCGDDLQQDQLTIQLIRIMNKMWLAERLDLKMVTFNCVPTGYKSGMIELVSEAETLRKIQVECGLTGSFKDRPIAEWLGKQNPSPLEYQSAVRNFTLSCAGYSVATYVLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRDRTPFVLTSDMAYVINGGDKPSTDFHYFVDLCCRAFNIVRKNADLLLHTLAHMATAGMPGVNSNAVQYVRRALLPSQSNPEAAATFAKMIQSSLKSWFTQFNFFLHNLAQMRFTPDEGSGELLSFVPRKYTMQQDGRLKIVKVVCFQKHYSMEKFYMYILEVTRHGQPDPTHLFRSYREFTEFHQKLCMHFPLVKLHSLPAGVHVGRSNIKSVAEKRLPLIQRFLKSLFDASEEIAHSELVYTFFHPLLRDQQEAKLGMPKIKEVKQQPSRDNPHEIGQIRLSLQYQRGVLTVMIHHAKGLPMLQGGQEPNTYVKCYLKPDPKKETKRKTKVVRKTCVPSFMETLEYRMPLNIIQERRLQVTVWSHDTLQENELLGGFDMDLSKYDLRQELVDWYRLGAVSRN

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
Q95RR5Q95RR5_DROMEPi3K68D366

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias39-63Polar residues
Compositional bias80-95Polar residues
Compositional bias268-299Polar residues
Compositional bias311-331Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE014296
EMBL· GenBank· DDBJ
AAF50011.1
EMBL· GenBank· DDBJ
Genomic DNA
AE014296
EMBL· GenBank· DDBJ
AAF50012.1
EMBL· GenBank· DDBJ
Genomic DNA
AY058587
EMBL· GenBank· DDBJ
AAL13816.1
EMBL· GenBank· DDBJ
mRNA
AE014296
EMBL· GenBank· DDBJ
ACZ94691.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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