Q7JWW6 · Q7JWW6_DROME
- ProteinAdenosine kinase
- GeneAdk3
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids366 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
function
ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
Catalytic activity
- adenosine + ATP = ADP + AMP + H+
Cofactor
Note: Binds 3 Mg2+ ions per subunit.
Pathway
Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenosine: step 1/1.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 327 | Proton acceptor | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | nucleus | |
Molecular Function | adenosine kinase activity | |
Molecular Function | ATP binding | |
Biological Process | AMP salvage | |
Biological Process | purine nucleobase metabolic process | |
Biological Process | purine ribonucleoside salvage |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAdenosine kinase
- EC number
- Short namesAK
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionQ7JWW6
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 73-365 | Carbohydrate kinase PfkB | ||||
Sequence: AAEASESSRCLTNPGGSALNTARILKQLGTDALFFGAVGADKHAEELRQIIRDRGIEARLQTVEDAHTGQCVCLMYQDNPTLYANIGASAQFEVQTLSHAVSHEGQSFLRPVERKQILYVEGFFVPQRSDVCDYIVQHLVRERRRLALNLSAPYIVRKNHQAMMKLARAAFFLFGNRQEFEALAEAAGGFRNVDELADHLLQSGGTKVIFVTNGSAGVQVITNYVEELAPPGPVSFEDFRAQRVEQLVDATGAGDAFVAGFLHAWLEKRSLGECIRMASSVAAKVVTQVGCNL |
Sequence similarities
Belongs to the carbohydrate kinase PfkB family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length366
- Mass (Da)40,365
- Last updated2006-10-03 v1
- ChecksumDF03ABF585B502D4
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE013599 EMBL· GenBank· DDBJ | AAF59279.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY102669 EMBL· GenBank· DDBJ | AAM27498.1 EMBL· GenBank· DDBJ | mRNA |