Q7JCZ7 · Q7JCZ7_MOUSE

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrial membrane
Molecular FunctionNADH dehydrogenase (ubiquinone) activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 6
  • EC number

Gene names

    • Name
      ND6
    • Synonyms
      mt-Nd6
      , Nd6

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Strains
    • AKR/J
    • WSB/EiJ
    • 129P3/J
    • BPH/2J
    • BPL/1J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q7JCZ7

Subcellular Location

Mitochondrion membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane36-66Helical
Transmembrane86-109Helical
Transmembrane142-167Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-18
ChainPRO_500771085319-172NADH-ubiquinone oxidoreductase chain 6

Structure

Family & Domains

Sequence similarities

Belongs to the complex I subunit 6 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    172
  • Mass (Da)
    18,626
  • Last updated
    2004-07-05 v1
  • Checksum
    55DE2331AB0A1115
MNNYIFVLSSLFLVGCLGLALKPSPIYGGLGLIVSGFVGCLMVLGFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPETWGSNWLILGFLVLGVIMEVFLICVLNYYDEVGVINLDGLGDWLMYEVDDVGVMLEGGIGVAAMYSCATWMMVVAGWSLFAGIFIIIEITRD

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
EF108344
EMBL· GenBank· DDBJ
ABK79286.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374639
EMBL· GenBank· DDBJ
ACM24370.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374640
EMBL· GenBank· DDBJ
ACM24383.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374641
EMBL· GenBank· DDBJ
ACM24396.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374642
EMBL· GenBank· DDBJ
ACM24409.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374643
EMBL· GenBank· DDBJ
ACM24422.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374644
EMBL· GenBank· DDBJ
ACM24435.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374646
EMBL· GenBank· DDBJ
ACM24461.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374647
EMBL· GenBank· DDBJ
ACM24474.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374648
EMBL· GenBank· DDBJ
ACM24487.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374649
EMBL· GenBank· DDBJ
ACM24500.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374650
EMBL· GenBank· DDBJ
ACM24513.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374651
EMBL· GenBank· DDBJ
ACM24526.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374652
EMBL· GenBank· DDBJ
ACM24539.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374653
EMBL· GenBank· DDBJ
ACM24552.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374654
EMBL· GenBank· DDBJ
ACM24565.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374655
EMBL· GenBank· DDBJ
ACM24578.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374656
EMBL· GenBank· DDBJ
ACM24591.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374657
EMBL· GenBank· DDBJ
ACM24604.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374658
EMBL· GenBank· DDBJ
ACM24617.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374659
EMBL· GenBank· DDBJ
ACM24630.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374660
EMBL· GenBank· DDBJ
ACM24643.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374661
EMBL· GenBank· DDBJ
ACM24656.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374662
EMBL· GenBank· DDBJ
ACM24669.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374663
EMBL· GenBank· DDBJ
ACM24682.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374664
EMBL· GenBank· DDBJ
ACM24695.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ374665
EMBL· GenBank· DDBJ
ACM24708.1
EMBL· GenBank· DDBJ
Genomic DNA
GQ871744
EMBL· GenBank· DDBJ
ACV90283.1
EMBL· GenBank· DDBJ
Genomic DNA
GQ871745
EMBL· GenBank· DDBJ
ACV90296.1
EMBL· GenBank· DDBJ
Genomic DNA
GQ871746
EMBL· GenBank· DDBJ
ACV90309.1
EMBL· GenBank· DDBJ
Genomic DNA
JX945964
EMBL· GenBank· DDBJ
AFX73491.1
EMBL· GenBank· DDBJ
Genomic DNA
JX945965
EMBL· GenBank· DDBJ
AFX73504.1
EMBL· GenBank· DDBJ
Genomic DNA
JX945966
EMBL· GenBank· DDBJ
AFX73517.1
EMBL· GenBank· DDBJ
Genomic DNA
JX945967
EMBL· GenBank· DDBJ
AFX73530.1
EMBL· GenBank· DDBJ
Genomic DNA
JX945968
EMBL· GenBank· DDBJ
AFX73543.1
EMBL· GenBank· DDBJ
Genomic DNA
JX945969
EMBL· GenBank· DDBJ
AFX73556.1
EMBL· GenBank· DDBJ
Genomic DNA
JX945970
EMBL· GenBank· DDBJ
AFX73569.1
EMBL· GenBank· DDBJ
Genomic DNA
JX945971
EMBL· GenBank· DDBJ
AFX73582.1
EMBL· GenBank· DDBJ
Genomic DNA
JX945972
EMBL· GenBank· DDBJ
AFX73595.1
EMBL· GenBank· DDBJ
Genomic DNA
JX945973
EMBL· GenBank· DDBJ
AFX73608.1
EMBL· GenBank· DDBJ
Genomic DNA
JX945974
EMBL· GenBank· DDBJ
AFX73621.1
EMBL· GenBank· DDBJ
Genomic DNA
JX945975
EMBL· GenBank· DDBJ
AFX73634.1
EMBL· GenBank· DDBJ
Genomic DNA
JX945976
EMBL· GenBank· DDBJ
AFX73647.1
EMBL· GenBank· DDBJ
Genomic DNA
JX945977
EMBL· GenBank· DDBJ
AFX73660.1
EMBL· GenBank· DDBJ
Genomic DNA
JX945979
EMBL· GenBank· DDBJ
AFX73686.1
EMBL· GenBank· DDBJ
Genomic DNA
KC663618
EMBL· GenBank· DDBJ
AGK29618.1
EMBL· GenBank· DDBJ
Genomic DNA
KC663622
EMBL· GenBank· DDBJ
AGK29671.1
EMBL· GenBank· DDBJ
Genomic DNA
KF937873
EMBL· GenBank· DDBJ
AHI52069.1
EMBL· GenBank· DDBJ
Genomic DNA
KF937874
EMBL· GenBank· DDBJ
AHI52081.1
EMBL· GenBank· DDBJ
Genomic DNA
KF937875
EMBL· GenBank· DDBJ
AHI52094.1
EMBL· GenBank· DDBJ
Genomic DNA
AB042432
EMBL· GenBank· DDBJ
BAA95627.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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