Q7EZZ0 · Q7EZZ0_ORYSJ

  • Protein
    UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

function

UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis, transfering GlcNAc-1-P from cytosolic UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol embedded in the cytoplasmic leaflet of the endoplasmic reticulum membrane.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Protein modification; protein glycosylation.

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum membrane
Cellular Componentmembrane
Molecular Functionglycosyltransferase activity
Molecular FunctionUDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity
Biological Processdolichol-linked oligosaccharide biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
  • EC number
  • Alternative names
    • GlcNAc-1-P transferase
    • N-acetylglucosamine-1-phosphate transferase

Gene names

    • ORF names
      OSNPB_070661100
    • Ordered locus names
      Os07g0661100

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Nipponbare
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Oryzoideae > Oryzeae > Oryzinae > Oryza > Oryza sativa

Accessions

  • Primary accession
    Q7EZZ0

Proteomes

Genome annotation databases

Subcellular Location

Endoplasmic reticulum membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane50-68Helical
Transmembrane80-105Helical
Transmembrane125-146Helical
Transmembrane158-177Helical
Transmembrane189-211Helical
Transmembrane288-309Helical
Transmembrane321-345Helical
Transmembrane403-425Helical

Keywords

PTM/Processing

Proteomic databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the glycosyltransferase 4 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    430
  • Mass (Da)
    47,012
  • Last updated
    2004-07-05 v1
  • Checksum
    0637129CC844076D
MDARRRPAATAAAAAAAPADAQPRARPAAAVAAAEAADAELVLRAPNLRVVAAAMVAFLAPFSYLAFVHYPLDAALRRSILICGAMSFGGFVVVLRLVPVAARYLLRRGMWGKDINKRGLPMGEIRVPEALGIVVGIVYLVIAILFQHFNFTADSMWLVEYNAALASVCFMVLLGFIDDVLDVPWRVKLLLPTIAALPLLMAYAGGTSVSIPKPLTSYVGVAVLELGSLYKLFMLLLAVFCTNSINIHAGLNGLEVGQTVIISAAVLIHNVMRIGSSTDIEAQQAHAFSIYLVLPFLTTSLALLAFNWYPSSVFVGDTYTYFSGMALAVVGILGHFSETLLLFFLPEVLNFLCSVPQLFKFVPCPRHRLPRFDPHTGLLTGTKDGNLVNIFLRIFGRCTERTLCIRLLIFQALSCLFCFWLRYMITGWYK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP014963
EMBL· GenBank· DDBJ
BAT03053.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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