Q7DJJ2 · Q7DJJ2_ECOLX
- ProteinShiga toxin 2, subunit B
- GenestxII
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
function
The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | extracellular region | |
Biological Process | hemolysis by symbiont of host erythrocytes |
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Escherichia
Accessions
- Primary accessionQ7DJJ2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-19 | |||||
Sequence: MKKMFMAVLFALVSVNAMA | ||||||
Chain | PRO_5015098708 | 20-89 | ||||
Sequence: ADCAKGKIEFSKYNEDDTFTVKVDGKEYWTSRWNLQPLLQSAQLTGMTVTIKSSTCESGSGFAEVQFNND | ||||||
Disulfide bond | 22↔75 | |||||
Sequence: CAKGKIEFSKYNEDDTFTVKVDGKEYWTSRWNLQPLLQSAQLTGMTVTIKSSTC |
Keywords
- PTM
Structure
Sequence
- Sequence statusComplete
- Length89
- Mass (Da)9,902
- Last updated2004-07-05 v1
- ChecksumC1198B5B6E5C0ACB
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AY443052 EMBL· GenBank· DDBJ | AAS07597.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY443054 EMBL· GenBank· DDBJ | AAS07601.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DQ143181 EMBL· GenBank· DDBJ | AAZ73246.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DQ231582 EMBL· GenBank· DDBJ | ABB52779.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DQ231583 EMBL· GenBank· DDBJ | ABB52781.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DQ231584 EMBL· GenBank· DDBJ | ABB52783.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DQ231585 EMBL· GenBank· DDBJ | ABB52785.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DQ231586 EMBL· GenBank· DDBJ | ABB52787.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DQ231587 EMBL· GenBank· DDBJ | ABB52789.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DQ231588 EMBL· GenBank· DDBJ | ABB52791.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DQ231591 EMBL· GenBank· DDBJ | ABB60213.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DQ231595 EMBL· GenBank· DDBJ | ABB60237.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
EF441620 EMBL· GenBank· DDBJ | ABR09965.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
EU526760 EMBL· GenBank· DDBJ | ACB37356.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
EU526761 EMBL· GenBank· DDBJ | ACB37358.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
EU526762 EMBL· GenBank· DDBJ | ACB37360.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
EU526763 EMBL· GenBank· DDBJ | ACB37362.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
EU526764 EMBL· GenBank· DDBJ | ACB37364.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
EU700491 EMBL· GenBank· DDBJ | ACD92979.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
GQ429161 EMBL· GenBank· DDBJ | ACU32683.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
GQ429162 EMBL· GenBank· DDBJ | ACU32685.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
GQ429163 EMBL· GenBank· DDBJ | ACU32687.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
GQ429168 EMBL· GenBank· DDBJ | ACU32697.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
GQ429169 EMBL· GenBank· DDBJ | ACU32699.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
GQ429170 EMBL· GenBank· DDBJ | ACU32701.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
HQ585062 EMBL· GenBank· DDBJ | ADV16384.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
KM516094 EMBL· GenBank· DDBJ | AIZ66855.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
KP120723 EMBL· GenBank· DDBJ | AJW83237.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB028899 EMBL· GenBank· DDBJ | BAA88601.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
Z37725 EMBL· GenBank· DDBJ | CAA85781.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AJ250954 EMBL· GenBank· DDBJ | CAC05527.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AJ251483 EMBL· GenBank· DDBJ | CAC05546.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AJ251520 EMBL· GenBank· DDBJ | CAC05550.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
FM998839 EMBL· GenBank· DDBJ | CAX45705.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
FM998842 EMBL· GenBank· DDBJ | CAX45711.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
FM998851 EMBL· GenBank· DDBJ | CAX45729.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
FM998852 EMBL· GenBank· DDBJ | CAX45731.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
FM998853 EMBL· GenBank· DDBJ | CAX45733.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
FM998854 EMBL· GenBank· DDBJ | CAX45735.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
FM998858 EMBL· GenBank· DDBJ | CAX45743.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
FM998859 EMBL· GenBank· DDBJ | CAX45745.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
FM998861 EMBL· GenBank· DDBJ | CAX45749.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
FR846369 EMBL· GenBank· DDBJ | CCA61210.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
FR846370 EMBL· GenBank· DDBJ | CCA61212.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
FR846372 EMBL· GenBank· DDBJ | CCA61216.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
FR846374 EMBL· GenBank· DDBJ | CCA61220.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
FR850031 EMBL· GenBank· DDBJ | CCA62488.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
FR874039 EMBL· GenBank· DDBJ | CCC15126.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
FR874040 EMBL· GenBank· DDBJ | CCC15131.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AASLUY010000024 EMBL· GenBank· DDBJ | EFE0301086.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AASLUY010000357 EMBL· GenBank· DDBJ | EFE0303214.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DABDSA010000048 EMBL· GenBank· DDBJ | HAI2144073.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DABDSA010000164 EMBL· GenBank· DDBJ | HAI2144433.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
VZEL01000062 EMBL· GenBank· DDBJ | KAB0121443.1 EMBL· GenBank· DDBJ | Genomic DNA |