Q76CU3 · Q76CU3_MOUSE
- Protein3beta-hydroxysteroid dehydrogenase VI
- GeneHsd3b6
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids373 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score1/5
Publications for Q76CU3
PRSS50 is a testis protease responsible for proper sperm tail formation and function.
- CategoriesFunction
- SourceMGI: 109598
Fetal Leydig cells dedifferentiate and serve as adult Leydig stem cells.
- CategoriesFunction, Expression
- SourceMGI: 109598
A potential role for zinc transporter 7 in testosterone synthesis in mouse Leydig tumor cells.
- AnnotationThe results demonstrated that ZnT7 gene silencing downregulated the expression of StAR P450scc and 3beta-HSD as well as progesterone concentrations in the human chorionic gonadotrophin-stimulated Leydig tumor cells.
- CategoriesFunction, Expression
- SourceGeneRif: 15497
Adrenal Development in Mice Requires GATA4 and GATA6 Transcription Factors.
- CategoriesFunction
- SourceMGI: 109598
Hypertension due to loss of clock: novel insight from the molecular analysis of Cry1/Cry2-deleted mice.
- Annotationa novel 3beta-hydroxyl-steroid dehydrogenase (3beta-Hsd) gene under clock control is severely overexpressed specifically in aldosterone-producing cells in the adrenal cortex leading to hyperaldosteronism and ultimately to salt-sensitive hypertension
- CategoriesFunction
- SourceGeneRif: 15497
Salt-sensitive hypertension in circadian clock-deficient Cry-null mice involves dysregulated adrenal Hsd3b6.
- Annotationwith Cry gene inactivation results in dyregulation and abnormally high plasma aldosterone concentration and salt-sensitive hypertension
- CategoriesFunction, Phenotypes & Variants
Mapped toGenetic determinants modulate susceptibility to pregnancy-associated tumourigenesis in a recombinant line of Min mice.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 109598