Q75N88 · Q75N88_HUMAN
- ProteinFibrillin 1
- GeneFBN1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1365 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | extracellular region | |
Cellular Component | microfibril | |
Molecular Function | calcium ion binding |
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionQ75N88
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-27 | |||||
Sequence: MRRGRLLEIALGFTVLLASYTSHGADA | ||||||
Chain | PRO_5004286877 | 28-1365 | ||||
Sequence: NLEAGNVKETRASRAKRRGGGGHDALKGPNVCGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLD | ||||||
Disulfide bond | 150↔160 | |||||
Sequence: CESGCLNGGRC | ||||||
Disulfide bond | 168↔177 | |||||
Sequence: CTYGFTGPQC | ||||||
Disulfide bond | 494↔504 | |||||
Sequence: CEKNPCAGGEC | ||||||
Disulfide bond | 811↔821 | |||||
Sequence: CESSPCINGVC |
Keywords
- PTM
Proteomic databases
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 146-178 | EGF-like | ||||
Sequence: GQPVCESGCLNGGRCVAPNRCACTYGFTGPQCE | ||||||
Domain | 184-227 | TB | ||||
Sequence: GPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQ | ||||||
Domain | 246-287 | EGF-like | ||||
Sequence: DVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCE | ||||||
Domain | 288-329 | EGF-like | ||||
Sequence: DIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCI | ||||||
Domain | 334-389 | TB | ||||
Sequence: GYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLC | ||||||
Domain | 490-525 | EGF-like | ||||
Sequence: DVDECEKNPCAGGECINNQGSYTCQCRAGYQSTLTR | ||||||
Domain | 530-571 | EGF-like | ||||
Sequence: DIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCE | ||||||
Domain | 572-612 | EGF-like | ||||
Sequence: DMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCK | ||||||
Domain | 613-653 | EGF-like | ||||
Sequence: DINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCV | ||||||
Domain | 659-711 | TB | ||||
Sequence: STCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALC | ||||||
Domain | 723-764 | EGF-like | ||||
Sequence: DINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCV | ||||||
Domain | 765-806 | EGF-like | ||||
Sequence: DINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCE | ||||||
Domain | 807-846 | EGF-like | ||||
Sequence: DIDECESSPCINGVCKNSPGSFICECSSESTLDPTKTICI | ||||||
Domain | 851-890 | TB | ||||
Sequence: GTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLC | ||||||
Domain | 910-951 | EGF-like | ||||
Sequence: DIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICL | ||||||
Domain | 956-1008 | TB | ||||
Sequence: ETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELC | ||||||
Domain | 1028-1069 | EGF-like | ||||
Sequence: DINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCT | ||||||
Domain | 1070-1112 | EGF-like | ||||
Sequence: DIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCM | ||||||
Domain | 1113-1154 | EGF-like | ||||
Sequence: DIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACI | ||||||
Domain | 1155-1196 | EGF-like | ||||
Sequence: DINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCV | ||||||
Domain | 1238-1279 | EGF-like | ||||
Sequence: DIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCV | ||||||
Domain | 1280-1317 | EGF-like | ||||
Sequence: DVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGK | ||||||
Domain | 1322-1362 | EGF-like | ||||
Sequence: DINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCT |
Sequence similarities
Belongs to the fibrillin family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,365
- Mass (Da)147,449
- Last updated2004-07-05 v1
- ChecksumED83FB79C1B2BD48