Q75BS3 · Q75BS3_EREGS

Function

function

The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

Pathway

Purine metabolism; purine nucleoside salvage.

Features

Showing features for binding site.

130820406080100120140160180200220240260280300
TypeIDPosition(s)Description
Binding site44phosphate (UniProtKB | ChEBI)
Binding site78phosphate (UniProtKB | ChEBI)
Binding site98-100phosphate (UniProtKB | ChEBI)
Binding site131phosphate (UniProtKB | ChEBI)
Binding site216a purine D-ribonucleoside (UniProtKB | ChEBI)
Binding site235phosphate (UniProtKB | ChEBI)
Binding site258a purine D-ribonucleoside (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular Functioninosine nucleosidase activity
Molecular Functionnicotinamide riboside hydrolase activity
Molecular Functionpurine-nucleoside phosphorylase activity
Biological Processguanosine catabolic process
Biological Processinosine catabolic process
Biological ProcessNAD biosynthesis via nicotinamide riboside salvage pathway
Biological Processnicotinate nucleotide salvage

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Purine nucleoside phosphorylase
  • EC number
  • Alternative names
    • Inosine-guanosine phosphorylase

Gene names

    • ORF names
      AGOS_ACR198W

Organism names

Accessions

  • Primary accession
    Q75BS3

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain38-305Nucleoside phosphorylase

Sequence similarities

Belongs to the PNP/MTAP phosphorylase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    308
  • Mass (Da)
    32,717
  • Last updated
    2004-07-05 v1
  • Checksum
    2B26D6BD7E0BE51A
MASFDINQERAVIQDAAEFLNGEITAHFGATCEFKPRVLIICGSGLGGISHVISSNPQPLSVPYSAIPGFKASTIVGHAGDLLFGFMNKTPVVLMKGRLHGYEGNTAQEITRPIRILNELGSIGVLVVTNAAGAVNPEFSACELMCINDHISFPGLCGFHPLRGPNFDETGPRFLATSDAYDLKLRQLLFSKHKELGIARRLHEGVYAHVSGPTFESRAESRLIRLVGADCVGMSTVPEVVVARHCGWRVLALSLITNCVVLSPAASALDTNPVPLDLGKAEHSEVIVNAAAASADVEQLVEAVVGAL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE016816
EMBL· GenBank· DDBJ
AAS51424.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp