Q750J0 · NPR3_EREGS
- ProteinNitrogen permease regulator 3
- GeneNPR3
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids940 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Mediates inactivation of the TORC1 complex in response to amino acid starvation. Required for meiotic nuclear division (By similarity).
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | GATOR1 complex | |
Biological Process | cellular response to amino acid starvation | |
Biological Process | meiotic cell cycle | |
Biological Process | negative regulation of TORC1 signaling | |
Biological Process | positive regulation of autophagy | |
Biological Process | TORC1 signaling |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameNitrogen permease regulator 3
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Saccharomycotina > Saccharomycetes > Saccharomycetales > Saccharomycetaceae > Eremothecium
Accessions
- Primary accessionQ750J0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-21 | |||||
Sequence: MYTNLPKACLTGIVLTISTHS | ||||||
Chain | PRO_0000301790 | 22-940 | Nitrogen permease regulator 3 | |||
Sequence: GPQVVYHYPPVKQPVEARRGRKVDSRNERVRSWQAGRMPSAASGAVDAVGEGVDGLEEESSESELDRSSGLSESEVSTDWADYSMSSSDSESEMREDGGGESSAVGGSSAAEGGEESLAEGADSSIAWPGPSESYNQLLESQSMVGSSANVAAASTKPKSIKSRHSQISANKLFQYLTNTSDADSRRQSVFSKLTGNEDSETIRLTDSVNLLDLESLLEDLEPGLADVDISELLDVEVFQPGRFQDVSKIFNFDAEFVAELCSPPKEMCNTRFELTVDDLCFLGLPIHVDESGRWRKQKVKRQQTNTRSKRSSSGGKPDAGSRTSVGLPHGTQERQPSTDQSGSGAPYLAQSSSESGQLRDPEQSDDVEDLQKAVHMFHVCFIMNPQLVEYNERIDDMYHYIVTRLSLILRYIQDKKGYVVRECAKILKTRDRILKKSLKLKKSHGQALQGRYLYECILKSSSLARALTKCFNSIINNEIVTLDIDNHKVISLQIPIKNEFSSLPDLKINPVLRGSYLTSLLNDSFLKQPVDFAAGSMMPGGDVMHDDNDVLDYALLLLDDTPKIIKDLEFSSFGSDLANVIMINLVKNLKPTVSLRSYLPLVSNLLEANLSLSARAAGSRHAASNAADSHSTPLQHSMIRSIVLHLVYWRYARIILPLSSKNTYIVSPLAPIRGTAADDFENTDMVKQGCKALIYQHQDLFHEKFPTLPTLPSFLSSISTCKPRSFGHLIPSKDHNLLYLSVLAWLIRYGYLTQLLTFVWLRVDRRIKIAVDEDLEREGVRTWNSIVKKEHRQNPHDNVAAPTREPASSAIDETASSSEHGDANISDGQESLDDYLFKESDYTIILEPKTATALEKRWLFKCIENQPTEMQLLFRKVIKYFNGKTPLELVEIKENIPKQELKKLIACLDKYVVELKHW |
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 37-52 | Basic and acidic residues | ||||
Sequence: EARRGRKVDSRNERVR | ||||||
Region | 37-155 | Disordered | ||||
Sequence: EARRGRKVDSRNERVRSWQAGRMPSAASGAVDAVGEGVDGLEEESSESELDRSSGLSESEVSTDWADYSMSSSDSESEMREDGGGESSAVGGSSAAEGGEESLAEGADSSIAWPGPSES | ||||||
Compositional bias | 91-109 | Polar residues | ||||
Sequence: GLSESEVSTDWADYSMSSS | ||||||
Region | 317-387 | Disordered | ||||
Sequence: RKQKVKRQQTNTRSKRSSSGGKPDAGSRTSVGLPHGTQERQPSTDQSGSGAPYLAQSSSESGQLRDPEQSD | ||||||
Compositional bias | 328-380 | Polar residues | ||||
Sequence: TRSKRSSSGGKPDAGSRTSVGLPHGTQERQPSTDQSGSGAPYLAQSSSESGQL | ||||||
Region | 812-848 | Disordered | ||||
Sequence: EHRQNPHDNVAAPTREPASSAIDETASSSEHGDANIS | ||||||
Compositional bias | 831-847 | Polar residues | ||||
Sequence: SAIDETASSSEHGDANI |
Sequence similarities
Belongs to the NPR3 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length940
- Mass (Da)104,770
- Last updated2013-01-09 v3
- ChecksumB684B45EE2D28587
Sequence caution
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 37-52 | Basic and acidic residues | ||||
Sequence: EARRGRKVDSRNERVR | ||||||
Compositional bias | 91-109 | Polar residues | ||||
Sequence: GLSESEVSTDWADYSMSSS | ||||||
Compositional bias | 328-380 | Polar residues | ||||
Sequence: TRSKRSSSGGKPDAGSRTSVGLPHGTQERQPSTDQSGSGAPYLAQSSSESGQL | ||||||
Compositional bias | 831-847 | Polar residues | ||||
Sequence: SAIDETASSSEHGDANI |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE016820 EMBL· GenBank· DDBJ | AAS54451.2 EMBL· GenBank· DDBJ | Genomic DNA | Different initiation |