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Q74ZB5 · EFM7_EREGS

Function

function

S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.

Features

Showing features for binding site.

126520406080100120140160180200220240260
TypeIDPosition(s)Description
Binding site67S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site93-95S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site115S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site152S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site176S-adenosyl-L-methionine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionN-terminal protein N-methyltransferase activity
Molecular Functionprotein-lysine N-methyltransferase activity
Biological ProcessN-terminal peptidyl-glycine methylation
Biological Processpeptidyl-lysine dimethylation
Biological ProcessrDNA heterochromatin formation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein N-terminal and lysine N-methyltransferase EFM7
  • EC number
  • Alternative names
    • Elongation factor methyltransferase 7

Gene names

    • Name
      EFM7
    • Synonyms
      NNT1
    • Ordered locus names
      AGR284W

Organism names

Accessions

  • Primary accession
    Q74ZB5

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000968891-265Protein N-terminal and lysine N-methyltransferase EFM7

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region1-25Disordered

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    265
  • Mass (Da)
    29,379
  • Last updated
    2004-07-05 v1
  • MD5 Checksum
    56154476DBB46BF8213C4104FC676C32
MSSDHEEDSLYGATELFGEPDGFYEKPAESHFAEYERSAVPAQSARRDTQVRIRLVGSSPLWGHLLWNSAIYTARHLDAHPEQVVGRCVLELGAAGALPSLVAGLLGARQVVATDYPDADLVGNIQYNVDHVIYGGKPPTEAPHVAVEGYIWGNDYGPLRRHLPPGQTGFDLVLLSDLVFNHTEHHKLLQTTRDLLAPAGRALVVFSPHRPWLLEKDLQFFETAAEYGLRAELIEQVTWAPMFADDPGPAEVRARVYAYYLTHCA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE016820
EMBL· GenBank· DDBJ
AAS54774.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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