Essential maintenance is planned to begin on Fri Jan 24 2025. The website may be temporarily unavailable. Please use our fallback: https://wwwdev.ebi.ac.uk/uniprot/front-end/fallback/ in case of any outage.

Q74K39 · Q74K39_LACJO

Function

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

132150100150200250300
Type
IDPosition(s)Description
Binding site96Zn2+ (UniProtKB | ChEBI)
Binding site113Zn2+ (UniProtKB | ChEBI)
Binding site170Zn2+ (UniProtKB | ChEBI)
Active site190

GO annotations

AspectTerm
Molecular Functionmannose-6-phosphate isomerase activity
Molecular Functionzinc ion binding
Biological Processcarbohydrate metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Mannose-6-phosphate isomerase
  • EC number

Gene names

    • Ordered locus names
      LJ_0916

Organism names

Accessions

  • Primary accession
    Q74K39

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain5-106Phosphomannose isomerase type I catalytic
Domain249-317Mannose-6-phosphate isomerase cupin

Sequence similarities

Belongs to the mannose-6-phosphate isomerase type 1 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    321
  • Mass (Da)
    36,395
  • Last updated
    2004-07-05 v1
  • MD5 Checksum
    C2C50F375F99E540EE9E360DF0E5422C
MEPLFLTPYFRPKIWGGRKLNTVLGYDIPDGKVGEAWVISGYKDDASIVNAGPFKGKTLREVYLEHPELFGNPKAKEFPLLVKFLDANDNLSVQVHPDDEYARIHENDSGKTESWYVLHAEPGAKLIYGHNAKSKEELEDWIKNGKWSKLLRYVPVKEGDFLYVPSGTVHALTKGTMVIETQQSSDVTYRLYDWDRVDKKTGKKRELHIKQSLDTIQVPHKDPKLKITSETVGDAKITTLAQPPMSPHFYLWQIDVDGDFAWSLNDHPYLLVSLIKGSGKFIADGKEYDIKLGSNFIIPNEMKNFSFSGNLRLVISAPGKE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE017198
EMBL· GenBank· DDBJ
AAS08737.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help