Essential maintenance is planned to begin on Fri Jan 24 2025. The website may be temporarily unavailable. Please use our fallback: https://wwwdev.ebi.ac.uk/uniprot/front-end/fallback/ in case of any outage.

Q74HW4 · Q74HW4_LACJO

Function

Catalytic activity

  • Release of the N-terminal residue from a tripeptide.
    EC:3.4.11.4 (UniProtKB | ENZYME | Rhea)

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 2 Zn2+ ions per subunit.

Features

Showing features for binding site, active site.

142450100150200250300350400
Type
IDPosition(s)Description
Binding site84Zn2+ 1 (UniProtKB | ChEBI)
Active site86
Binding site144Zn2+ 2 (UniProtKB | ChEBI)
Binding site144Zn2+ 1 (UniProtKB | ChEBI)
Active site178Proton acceptor
Binding site179Zn2+ 2 (UniProtKB | ChEBI)
Binding site201Zn2+ 1 (UniProtKB | ChEBI)
Binding site383Zn2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionmetallopeptidase activity
Molecular Functiontripeptide aminopeptidase activity
Molecular Functionzinc ion binding
Biological Processpeptide metabolic process
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Peptidase T
  • EC number

Gene names

    • Ordered locus names
      LJ_0645

Organism names

Accessions

  • Primary accession
    Q74HW4

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain211-310Peptidase M20 dimerisation

Sequence similarities

Belongs to the peptidase M20B family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    424
  • Mass (Da)
    47,044
  • Last updated
    2004-07-05 v1
  • MD5 Checksum
    FFD1AF41CBB3032BA9D9424DBFB58A40
MPEIDQKYIQNKFIEYCKVNTRSDEQSTAVPTTAGQVDLLKIIEKELEKLGLENISFSEEDSYLVGKLKKTTKKEVTPIGFVAHVDTADFNAENVKPLVHQNYDGKDIFLKEGRVLSTSEFPSLKKHLGETLITADGTTLLGADDKAGIAGLLGMLKLLKENPYLEHGDIWVAFGPDEEIGKGAARFNVERFPVEFAYTLDNGDPGDIAFETFNAAAATIDFHGTVVHPGEAYGLMVNAALIASEFIQALPGSEVPENSKDFDGYFMVLSNNGNVDYAKIQLIIRDFDTDGFEQKKKLITGTVDKLNKKYGTNRVTFEMHDQYHSPGDLIKEHPYVVNLVLHAYKSLGLEPKVIPFRGGTDGDFISEKGIPTPNLFNGGANFHGPYEYVTTESMALLAKTLIEIAKQHVLLNDKRDESPLKRKY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE017198
EMBL· GenBank· DDBJ
AAS09576.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help