Q71VM4 · IMA1A_ORYSJ

Function

function

Functions in nuclear protein import. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Promotes docking of import substrates to the nuclear envelope.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Cellular Componentperinuclear region of cytoplasm
Molecular Functionnuclear import signal receptor activity
Molecular Functionnuclear localization sequence binding
Biological ProcessNLS-bearing protein import into nucleus

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Importin subunit alpha-1a

Gene names

    • Ordered locus names
      Os01g0253300, LOC_Os01g14950

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Nipponbare
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Oryzoideae > Oryzeae > Oryzinae > Oryza > Oryza sativa

Accessions

  • Primary accession
    Q71VM4
  • Secondary accessions
    • O82783

Proteomes

Genome annotation databases

Subcellular Location

PTM/Processing

Features

Showing features for chain, modified residue (large scale data).

TypeIDPosition(s)SourceDescription
ChainPRO_00001207401-526UniProtImportin subunit alpha-1a
Modified residue (large scale data)105PTMeXchangePhosphoserine
Modified residue (large scale data)189PTMeXchangePhosphoserine

Proteomic databases

Expression

Tissue specificity

Highly expressed in callus, followed by root and etiolated leaf. Low expression in green leaf.

Induction

In both etiolated and green leaves, down-regulated by light. In green leaf, increased by dark treatment.

Gene expression databases

Interaction

Subunit

Forms a complex with importin subunit beta-1. The whole complex, most stable and composed of importin alpha, importin beta and NLS substrate, is referred to as PTAC or pore targeting complex. Interacts with mungbean yellow mosaic virus capsid protein.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, repeat.

TypeIDPosition(s)Description
Domain1-58IBB
Repeat105-145ARM 1
Repeat148-187ARM 2
Repeat190-230ARM 3
Repeat232-271ARM 4
Repeat274-313ARM 5
Repeat316-356ARM 6
Repeat359-398ARM 7
Repeat402-441ARM 8

Sequence similarities

Belongs to the importin alpha family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    526
  • Mass (Da)
    57,571
  • Last updated
    2005-04-26 v2
  • Checksum
    7A7DA264968FC983
MSLRPSERVEVRRNRYKVAVDAEEGRRRREDNMVEIRKSRREESLLKKRREGLQAQAPVPASAATGVDKKLESLPAMIGGVYSDDNNLQLEATTQFRKLLSIERSPPIEEVIQSGVVPRFVQFLTREDFPQLQFEAAWALTNIASGTSENTKVVIDHGAVPIFVKLLGSSSDDVREQAVWALGNVAGDSPKCRDLVLANGALLPLLAQLNEHTKLSMLRNATWTLSNFCRGKPQPSFEQTRPALPALARLIHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDAQTQCIIDHQALPCLLSLLTQNLKKSIKKEACWTISNITAGNKDQIQAVINAGIIGPLVNLLQTAEFDIKKEAAWAISNATSGGSHDQIKYLVSEGCIKPLCDLLICPDIRIVTVCLEGLENILKVGETDKTLAAGDVNVFSQMIDEAEGLEKIENLQSHDNNEIYEKAVKILEAYWMDEEDDTMGATTVAAPQGATFDFGQGGGAAQFK

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict473-474in Ref. 2; AAQ13406

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB004660
EMBL· GenBank· DDBJ
BAA31165.1
EMBL· GenBank· DDBJ
mRNA
AF005265
EMBL· GenBank· DDBJ
AAQ13406.1
EMBL· GenBank· DDBJ
mRNA
AB004814
EMBL· GenBank· DDBJ
BAA31166.1
EMBL· GenBank· DDBJ
Genomic DNA
AP000816
EMBL· GenBank· DDBJ
BAA87855.1
EMBL· GenBank· DDBJ
Genomic DNA
AP014957
EMBL· GenBank· DDBJ
BAS71366.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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