Q70G35 · Q70G35_9STAP
- ProteinMercuric reductase
- GenemerA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids501 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- Hg + NADP+ + H+ = Hg2+ + NADPH
Cofactor
Note: Binds 1 FAD per subunit.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 112 | FAD (UniProtKB | ChEBI) | |||
Binding site | 237-244 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 327 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 368 | FAD (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | flavin adenine dinucleotide binding | |
Molecular Function | mercury (II) reductase (NADP+) activity | |
Molecular Function | mercury ion binding | |
Molecular Function | NADP binding | |
Molecular Function | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor | |
Biological Process | detoxification of mercury ion |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMercuric reductase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Staphylococcaceae > Staphylococcus
Accessions
- Primary accessionQ70G35
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Disulfide bond | 103↔108 | Redox-active | |||
Keywords
- PTM
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 66-383 | FAD/NAD(P)-binding | |||
Domain | 403-501 | Pyridine nucleotide-disulphide oxidoreductase dimerisation | |||
Sequence similarities
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length501
- Mass (Da)53,889
- Last updated2004-07-05 v1
- MD5 ChecksumC1A87D5B2FD77E9B1CE0E1556201D4E7
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Non-terminal residue | 1 | ||||
Non-terminal residue | 501 | ||||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AJ582649 EMBL· GenBank· DDBJ | CAE46810.1 EMBL· GenBank· DDBJ | Genomic DNA |