Q6ZMY6 · WDR88_HUMAN

  • Protein
    WD repeat-containing protein 88
  • Gene
    WDR88
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    WD repeat-containing protein 88
  • Alternative names
    • PQQ repeat and WD repeat-containing protein

Gene names

    • Name
      WDR88
    • Synonyms
      PQWD

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    Q6ZMY6
  • Secondary accessions
    • Q8NEF8

Proteomes

Organism-specific databases

Disease & Variants

Features

Showing features for natural variant.

TypeIDPosition(s)Description
Natural variantVAR_035892166in a breast cancer sample; somatic mutation
Natural variantVAR_032030310in dbSNP:rs11881580

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 537 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Organism-specific databases

Miscellaneous

Genetic variation databases

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002856301-472WD repeat-containing protein 88

Proteomic databases

PTM databases

Expression

Gene expression databases

Organism-specific databases

Interaction

Binary interactions

Protein-protein interaction databases

Miscellaneous

Structure

Family & Domains

Features

Showing features for region, repeat, compositional bias.

TypeIDPosition(s)Description
Region1-22Disordered
Repeat100-139WD 1
Repeat143-182WD 2
Repeat184-224WD 3
Repeat228-267WD 4
Repeat271-310WD 5
Repeat319-358WD 6
Repeat361-400WD 7
Compositional bias447-463Polar residues
Region447-472Disordered

Keywords

Phylogenomic databases

Family and domain databases

Sequence & Isoform

Align isoforms (2)
  • Sequence status
    Complete

This entry describes 2 isoforms produced by Alternative splicing.

Q6ZMY6-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    472
  • Mass (Da)
    52,621
  • Last updated
    2010-05-18 v2
  • Checksum
    B525CCC29477F730
MASPPRCSPTAHDRECKLPPPSAPASEYCPGKLSWGTMARALGRFKLSIPHTHLLATLDPLALDREPPPHLLPEKHQVPEKLIWGDQDPLSKIPFKILSGHEHAVSTCHFCVDDTKLLSGSYDCTVKLWDPVDGSVVRDFEHRPKAPVVECSITGDSSRVIAASYDKTVRAWDLETGKLLWKVRYDTFIVSCKFSPDGKYVVSGFDVDHGICIMDAENITTVSVIKDHHTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHSNAISNCCFTFSGHFLCTSSWDKNLKIWNVHTGEFRNCGACVTLMQGHEGSVSSCHFARDSSFLISGGFDRTVAIWDVAEGYRKLSLKGHNDWVMDVAISNNKKWILSASKDRTMRLWNIEEIDEIPLVIKYKKAVGLKLKQCERCDRPFSIFKSDTSSEMFTQCVFCRIDTRGLPADTSSSSSSSERENSPPPRGSKDD

Q6ZMY6-2

  • Name
    2
  • See also
    sequence in UniParc or sequence clusters in UniRef
  • Differences from canonical
    • 415-472: CERCDRPFSIFKSDTSSEMFTQCVFCRIDTRGLPADTSSSSSSSERENSPPPRGSKDD → EKKEAYLKLKQG

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
K7EPH1K7EPH1_HUMANWDR88164

Sequence caution

The sequence AAH31227.2 differs from that shown. Reason: Erroneous initiation Extended N-terminus.

Features

Showing features for alternative sequence, compositional bias.

TypeIDPosition(s)Description
Alternative sequenceVSP_024873415-472in isoform 2
Compositional bias447-463Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AK131444
EMBL· GenBank· DDBJ
BAD18589.1
EMBL· GenBank· DDBJ
mRNA
AC008738
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
BC031227
EMBL· GenBank· DDBJ
AAH31227.2
EMBL· GenBank· DDBJ
mRNA Different initiation

Genome annotation databases

Similar Proteins

Disclaimer

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